Neck - Part 4 Flashcards

1
Q

T4

A

Thyroxine

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2
Q

What is the normal range for thyroxine?

A

4.5-12ug/dL

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3
Q

What does T4 do?

A

Stimulates consumption of oxygen

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4
Q

What is thyroxine secreted by?

A

Follicular cells of the thyroid

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5
Q

What is T4 controlled by?

A

Thyrotropin

- TSH

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6
Q

What amount of iodine needs to be ingested per week for normal thyroxine production?

A

100-200mg

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7
Q

What is decrease of T4 associated with? (2)

A
  1. Thyroid disease

2. Nonfunctioning pituitary gland

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8
Q

T3

A

Triiodothyronine

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9
Q

What is the normal range for triiodothyronine?

A

70-190ng/dL

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10
Q

What does T3 do?

A

Regulates tissue metabolism

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11
Q

What is decreased amounts of triiodothyronine associated with?

A

Hashimoto thyroiditis

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12
Q

What is the normal range for calcitonin?

A

< 100pg/mL

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13
Q

What does calcitonin do?

A

Lowers calcium and phosphorus concentration in the blood

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14
Q

What does calcitonin inhibit?

A

Bone resorption

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15
Q

What is calcitonin secreted by?

A

Parafollicular cells

- C-cells of the thyroid gland

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16
Q

What is elevated amounts of calcitonin associated with?

A

Medullary thyroid carcinoma

17
Q

What are decrease levels of calcitonin associated with? (2)

A
  1. Surgical removal of the thyroid glands

2. Nonfunctioning thyroid glands

18
Q

PTH

A

Parathormone

- parathyroid hormone

19
Q

What is the normal range of parathormone?

A

12-68pg/mL

20
Q

What does PTH do?

A

Regulates calcium metabolism in conjunction with calcitonin

21
Q

Why is parathormone released in response to?

A

To low extracellular concentration of free calcium

22
Q

What is elevation of PTH associated with?

A

Hyperparathyroidism

23
Q

What is the normal range of calcium?

A

8.5-10.5mg/dL

24
Q

What does calcium aid in?

A

The transportation of nutrients through the cell membranes

25
What is elevation of calcium associated with? (3)
1. hyperparathyroidism 2. Hyperthyroidism 3. Malignancy
26
What levels of calcium is considered life threatening?
14.5mg/dL
27
What are decrease levels of calcium associated with? (2)
1. Nonfunctioning parathyroid glands | 2. Surgical removal of the parathyroid glands
28
Hyperthyroidism
Hyperactivity of the thyroid gland
29
What are the symptoms of hyperthyroidism? (9)
1. Nervousness 2. Exophthalmos 3. Tremors 4. Constant hunger 5. Weight loss 6. Heat intolerance 7. Palpitations 8. Increased heart rate 9. Diarrhea
30
What are the causes of hyperthyroidism? (3)
1. Toxic adenoma 2. Graves disease 3. Trophoblastic tumours
31
What can happen if hyperthyroidism goes untreated?
May lead to cardiac failure
32
What is the percentage of thyroid nodules that are benign?
60%
33
What is the percentage of thyroid nodules that are cysts?
20%
34
What is the percentage of thyroid nodules that are malignant?
20%