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Flashcards in Neisseria Deck (20):
0

Structural elements of N. meningitidis and N. gonorrhoeae are same except that one of then has a polysaccharide capsule external to the cell wall. Which one?

N. meningitidis

1

N. meningitidis and N. gonorrhoeae Which one is more fastidious?

N. gonorrhoeae

2

N. meningitidis serogroup __ causes widespread epidemics

A

3

Serogroups of N.meningitidis are based on
A. Outer membrane proteins
B. Polysaccharide capsule
C. Both of the above
D. None of the above

Serogroups are based on OMP’s and polysaccharide capsule

Answer: C

4

False about N.meningitidis
A.Transmission by inhalation of aerosolized respiratory droplets
B. Infection is highest among infants
C. zoonotic disease happens more often because of this bacteria
D. None of those mentioned

C

Human: only natural host

5

Which is not a virulence factor of N.meningitidis?
A. Capsule
B. Lipooligosaccharide
C. IgE protease
D. Outer membrane proteins

C

IgA dapat

6

A.enters epithelium through membrane-bound vesicles
B.Pili attaches to CD46 protein of epithelial cells
C.damages cell by releasing endotoxin, travels through cell
D.exits cell to bloodstream
E. Bacteremia and invasion of CNS

Arrange steps in pathogenesis of N.meningitidis

B A C D E

7

N.meningitidis grows in the ff except
A. Blood Agar Plate
B. Chocolate Agar
C. Bordet - Gengou Medium
D. None of the above

C

8

First choice treatment drug for N.meningitidis

Penicillin

9

Prophylaxis antibiotics for N.meningitidis

Rifampin, Ciprofloxacin

10

Transmission of N.gonorrheae

Sexually transmitted

11

Neisseria stick to mucous secretions and non-ciliated cells by their __ and __

Neisseria stick to mucous secretions and non-ciliated cells by their pili and Opa proteins

12

___ of pili, Opa proteins and LOS enables gonococci to escape immune surveillance

Antigenic variation of pili, Opa proteins and LOS enables gonococci to escape immune surveillance

13

False about N.gonorrheae
A.Anaerobic
B.Converts glucose to acetic acid
C.Capnophilic-
D.Require iron and nitrogen for growth -

A

aerobic dapat

14

N.gonorrheae is said to be auxotrophic. What does this mean?

require one or more substances for growth

15

Pathogenesis of N.gonorrheae: fill in the blanks

Initial attachment mediated by ___ Tighter attachment mediated by ___

Pili
Opa proteins

16

__ trigger signaling cascade to induce phagocytosis of bacterial cell
A. Pili
B. Lipopolysaccharide
C. Opa proteins

C

17

Ingestion and transport through epithelium is ___ to that of meningococci
A. Similar
B. Different
C. Varied

A

18

What is parasite-mediated endocytosis?

Microbe tells microvilli via signals to phagocytose the said bacteria

19

Mechanism of N.gonorrheae that downplays complement activation and makes it act like capsule

LOS Sialyation