Rubella

Question 1

genus of Rubella

Answer 1

Rubivirus

Question 2

false about Rubella
A.one antigenic type
B.naked virus
C.single strand positive sense RNA
D.icosahedral nucleocapsid

Answer 2

B

enveloped dapat

Question 3

Rubella glycoprotein components: enumerate

Answer 3

E1
E2
host cell derived lipid

Question 4

icosahedral nucleocapsid components:enumerate

Answer 4

C protein

ssRNA

Question 5

enumerate 3 major virion polypeptides of rubella virus

Answer 5

C protein
E1
E2

Question 6

antigen in rubella that agglutinates chick, pigeon, goose and type O human RBC

Answer 6

Hemagglutinating Ag

Question 7

Where does rubella virus replicate?

Answer 7

cytoplasm

Question 8

Which is false?
A. Rubella is zoonotic.
B. Rubella may be transmitted via inhalational or transplacental.
C. Peak of rubella infection is during late winter and spring.
D. Rubella is communicable 7 days before and after the onset.

Answer 8

A

humans: only host

Question 9

In postnatal rubella, in what organ does the virus replicate?

Answer 9

nasopharynx

Question 10

T or F: Placenta and fetus may be infected in viremia of postnatal rubella.

Answer 10

T

Question 11

Sequence the clinical features of rubella
A. Maculopapular rash
B. Prodromal
C. Lymphadenopathy

Answer 11

B C A

Question 12

Identify enanthem of rubella + locatiion

Answer 12

Forschheimer spots @ soft palate

Question 13

most common complication of postnatal rubella

Answer 13

arthralgia/arthritis

Question 14

False about Rubella reinfection
A. occurs in a person with natural rubella or vaccine
B. IgG antibody response is higher with equiocal IgM titer
C. uncommon to cause unequivocal fetal damage
D. with visible symptoms

Answer 14

D

Question 15

most common manif of Congenital Rubella Syndrome

Answer 15

intrauterine growth retardation

Question 16

most common clinical feature of Congenital Rubella Syndrome

Answer 16

deafness

Question 17

[Congenital Rubella]

slow cell div, disoriented cell diff, small BV damages: in what trim does this occur?

Answer 17

1st

Question 18

Specific Ig @ less than __ months indicates (+) Congenital Rubella

Answer 18

12

if 9-12 months, check if there’s maternal Ab inteference

Question 19

method of choice for Congenital Rubella diagnosis indluse all except:
A.virus isolation
B.ELISA
C.immunofluorescent absorbent assay

Answer 19

A

Question 20

passive prophylaxis of rubella

Answer 20

human immunoglobulin

Question 21

live virus for rubella artificial active immunity – what is the composition?

Answer 21

RA 27/3 Strain

Question 22

ELISA may be used to measure Ig\_\_
A. G
B. A
C. E
D. M

Answer 22

D