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Flashcards in Rubella Deck (22):
1

genus of Rubella

Rubivirus

2

false about Rubella
A.one antigenic type
B.naked virus
C.single strand positive sense RNA
D.icosahedral nucleocapsid

B

enveloped dapat

3

Rubella glycoprotein components: enumerate

E1
E2
host cell derived lipid

4

icosahedral nucleocapsid components:enumerate

C protein
ssRNA

5

enumerate 3 major virion polypeptides of rubella virus

C protein
E1
E2

6

antigen in rubella that agglutinates chick, pigeon, goose and type O human RBC

Hemagglutinating Ag

7

Where does rubella virus replicate?

cytoplasm

8

Which is false?
A. Rubella is zoonotic.
B. Rubella may be transmitted via inhalational or transplacental.
C. Peak of rubella infection is during late winter and spring.
D. Rubella is communicable 7 days before and after the onset.

A

humans: only host

9

In postnatal rubella, in what organ does the virus replicate?

nasopharynx

10

T or F: Placenta and fetus may be infected in viremia of postnatal rubella.

T

11

Sequence the clinical features of rubella
A. Maculopapular rash
B. Prodromal
C. Lymphadenopathy

B C A

12

Identify enanthem of rubella + locatiion

Forschheimer spots @ soft palate

13

most common complication of postnatal rubella

arthralgia/arthritis

14

False about Rubella reinfection
A. occurs in a person with natural rubella or vaccine
B. IgG antibody response is higher with equiocal IgM titer
C. uncommon to cause unequivocal fetal damage
D. with visible symptoms

D

15

most common manif of Congenital Rubella Syndrome

intrauterine growth retardation

16

most common clinical feature of Congenital Rubella Syndrome

deafness

17

[Congenital Rubella]
slow cell div, disoriented cell diff, small BV damages: in what trim does this occur?

1st

18

Specific Ig @ less than __ months indicates (+) Congenital Rubella

12


if 9-12 months, check if there's maternal Ab inteference

19

method of choice for Congenital Rubella diagnosis indluse all except:
A.virus isolation
B.ELISA
C.immunofluorescent absorbent assay

A

20

passive prophylaxis of rubella

human immunoglobulin

21

live virus for rubella artificial active immunity -- what is the composition?

RA 27/3 Strain

22

ELISA may be used to measure Ig__
A. G
B. A
C. E
D. M

D