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Flashcards in Neoplasms and Cancer Deck (47):
1

Aggressive lung tumors that metastasize widely, especially to the brain

Small cell carcinoma

2

Benign or malignant? Cytologic uniformity

Benign

3

Benign or malignant? general loss of boundary between tumor and adjacent tissue

Malignant

4

Benign or malignant? Invasive, metastasizes

Malignant

5

Benign or malignant? cause injury both by local tissue destruction and distant dissemination and tissue destruction

Malignant

6

Benign or malignant? circumscribed/encapsulated

Benign

7

Benign or malignant? High rate of cell turnover

Malignant

8

Benign or malignant? injury by compression interference of adjacent structures

Benign

9

Benign or malignant? Necrosis

Malignant

10

Benign or malignant? well differentiated

Benign

11

Bind to interior surface of microtubule, stabilize microtubule against de-polymerization

Taxanes

12

Bind to tubulin at ends, stabilizing them

Vinca Alkaloids

13

In ______ tissues, there is little or no capacity for proliferation

non-dividing

14

In ______ tissues, there is normally little or no turnover but there is capacity for proliferation if needed

quiescent

15

Lung carcinoma characterized by cells attempting to form primitive gland-like structures (stain positive for mucin)

Adenocarcinoma

16

Lung carcinoma characterized by metaplasia of pseudostratified ciliated columnar epithelium to squamous epithelium

Squamous cell carcinoma

17

Moderately well differentiated adenocarcinomas arising in mucosal layer of bowel

Colorectal carcinoma

18

Name the drug class: 5-Flurouracil

Anti-metabolite

19

Name the drug class: Anthracyclines

Topoisomerase Inhibitor

20

Name the drug class: Aromatase Inhibitors

Hormonal Agents

21

Name the drug class: Bicalutamide

Hormonal Agents

22

Name the drug class: Carboplatin

Cisplatin Analogue

23

Name the drug class: Etosopide

Topoisomerase Inhibitor

24

Name the drug class: Flutamide

Hormonal Agents

25

Name the drug class: GNHR Analgoues

Hormonal Agents

26

Name the drug class: Herceptin

Antibody

27

Name the drug class: Imatinib

Kinase Inhibitor

28

Name the drug class: Methotrexate

Anti-metabolite

29

Name the drug class: Nitrogen Mustard

Alkylating Agent

30

Name the drug class: Oxaliplatin

Cisplatin Analogue

31

Name the drug class: Rituximab

Antibody

32

Name the drug class: Tamoxifen

Hormonal Agents

33

Name the drug class: Taxanes

Anti-Microtubule Agent

34

Name the drug class: Vinblastine

Anti-Microtubule Agent

35

Name the drug class: Vincristine

Anti-Microtubule Agent

36

Pyrimidine Analog that is metabolized by thymidine kinase and inhibits DNA synthesis

5-Fluorouracil

37

Reversible, competitive inhibitor of DHFR, which is required for purine nucleotide synthesis

Methotrexate

38

Tumor Stage: T1/T2, N0, M0

I

39

Tumor Stage: T1/T2, N1, M0

IIIA

40

Tumor Stage: T3, N0, M0

IIA

41

Tumor Stage: T3/T4, N2, M0

IIIB

42

Tumor Stage: T4, N0, M0

IIB

43

Tumor Stage: Tany, N2, M0

IIIC

44

Tumor Stage: Tany, Nany, M1

IV

45

Types of lung carcinoma most linked to smoking

Small cell and squamous cell

46

Undifferentiated high grade lung cancer where cells may not produce keratin or mucin

Large cell carcinoma

47

What type of malignant tumor is characterized by having a pre-malignant lesion and an in-situ phase?

Carcinoma