Neoplasms and Cancer Flashcards

(47 cards)

1
Q

Aggressive lung tumors that metastasize widely, especially to the brain

A

Small cell carcinoma

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2
Q

Benign or malignant? Cytologic uniformity

A

Benign

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3
Q

Benign or malignant? general loss of boundary between tumor and adjacent tissue

A

Malignant

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4
Q

Benign or malignant? Invasive, metastasizes

A

Malignant

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5
Q

Benign or malignant? cause injury both by local tissue destruction and distant dissemination and tissue destruction

A

Malignant

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6
Q

Benign or malignant? circumscribed/encapsulated

A

Benign

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7
Q

Benign or malignant? High rate of cell turnover

A

Malignant

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8
Q

Benign or malignant? injury by compression interference of adjacent structures

A

Benign

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9
Q

Benign or malignant? Necrosis

A

Malignant

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10
Q

Benign or malignant? well differentiated

A

Benign

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11
Q

Bind to interior surface of microtubule, stabilize microtubule against de-polymerization

A

Taxanes

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12
Q

Bind to tubulin at ends, stabilizing them

A

Vinca Alkaloids

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13
Q

In ______ tissues, there is little or no capacity for proliferation

A

non-dividing

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14
Q

In ______ tissues, there is normally little or no turnover but there is capacity for proliferation if needed

A

quiescent

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15
Q

Lung carcinoma characterized by cells attempting to form primitive gland-like structures (stain positive for mucin)

A

Adenocarcinoma

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16
Q

Lung carcinoma characterized by metaplasia of pseudostratified ciliated columnar epithelium to squamous epithelium

A

Squamous cell carcinoma

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17
Q

Moderately well differentiated adenocarcinomas arising in mucosal layer of bowel

A

Colorectal carcinoma

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18
Q

Name the drug class: 5-Flurouracil

A

Anti-metabolite

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19
Q

Name the drug class: Anthracyclines

A

Topoisomerase Inhibitor

20
Q

Name the drug class: Aromatase Inhibitors

A

Hormonal Agents

21
Q

Name the drug class: Bicalutamide

A

Hormonal Agents

22
Q

Name the drug class: Carboplatin

A

Cisplatin Analogue

23
Q

Name the drug class: Etosopide

A

Topoisomerase Inhibitor

24
Q

Name the drug class: Flutamide

A

Hormonal Agents

25
Name the drug class: GNHR Analgoues
Hormonal Agents
26
Name the drug class: Herceptin
Antibody
27
Name the drug class: Imatinib
Kinase Inhibitor
28
Name the drug class: Methotrexate
Anti-metabolite
29
Name the drug class: Nitrogen Mustard
Alkylating Agent
30
Name the drug class: Oxaliplatin
Cisplatin Analogue
31
Name the drug class: Rituximab
Antibody
32
Name the drug class: Tamoxifen
Hormonal Agents
33
Name the drug class: Taxanes
Anti-Microtubule Agent
34
Name the drug class: Vinblastine
Anti-Microtubule Agent
35
Name the drug class: Vincristine
Anti-Microtubule Agent
36
Pyrimidine Analog that is metabolized by thymidine kinase and inhibits DNA synthesis
5-Fluorouracil
37
Reversible, competitive inhibitor of DHFR, which is required for purine nucleotide synthesis
Methotrexate
38
Tumor Stage: T1/T2, N0, M0
I
39
Tumor Stage: T1/T2, N1, M0
IIIA
40
Tumor Stage: T3, N0, M0
IIA
41
Tumor Stage: T3/T4, N2, M0
IIIB
42
Tumor Stage: T4, N0, M0
IIB
43
Tumor Stage: Tany, N2, M0
IIIC
44
Tumor Stage: Tany, Nany, M1
IV
45
Types of lung carcinoma most linked to smoking
Small cell and squamous cell
46
Undifferentiated high grade lung cancer where cells may not produce keratin or mucin
Large cell carcinoma
47
What type of malignant tumor is characterized by having a pre-malignant lesion and an in-situ phase?
Carcinoma