Neuroscience Week 7: Frontal Lobes Flashcards

(62 cards)

1
Q

Phineas Gage

A
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2
Q

Bedlam 1946

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3
Q

Early Psychosurgery pioneers

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4
Q

Moniz Technique

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5
Q

Walter Freeman

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6
Q

Freeman’s first patients

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7
Q

Clinical efficacy of lobotomy

A

positive and negative

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8
Q

Transorbital lobotomy history

A
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9
Q

Transorbital lobotomy photographs

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10
Q

Rapid decline of lobotomy

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11
Q

Modern day psychosurgery

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12
Q

Noninvasive brain stimulation

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13
Q

Frontal lobe anatomy

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14
Q

Identify

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15
Q

BA 4

A

Primary motor strip

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16
Q

BA 6

A

supplementary motor cortex

&

Premotor cortex

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17
Q

BA 9, 10, 46

A

Dorsolateral prefrontal

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18
Q

BA 24, 25, 32, 33

A

Medial frontal

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19
Q

BA 47, 11, 12

A

Orbital frontal

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20
Q

Phylogenetic expansion of the frontal lobes

6 listed

A
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21
Q

Otogenetic expansion of the frontal lobes

4 listed

A
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22
Q

Subcortical structures of the frontal lobes

5 listed

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23
Q

Basal Ganglia structures

5 listed

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24
Q

Identify

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25
Frontal-subcortical circuits 5 listed
* parallel * segregated * functional * closed * open
26
Parallel circuit description
each circuit has the same structures as the others
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Segregated circuit description
each circuit is distinct from the others
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Functional circuit description
Each one serves a different function
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Closed circuit description
returning to original cortical area
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Open circuit description
receiving input from areas outside the circuit
31
Identify
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Three of the Frontal-subcortical circuits
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Behavior circuits ______ motor circuits
mirror
34
Direct and indirect pathway
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Modulation of thalamic discharge direct and indirect pathways
36
The medial frontal circuit AKA
anterior cingulate circuit
37
The medial frontal circuit function
responsible for motivation and deciding
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anterior cingulate circuit function
responsible for motivation and deciding
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Orbital frontal circuit function
responsible for social behavior and reward/punishment assessment
40
Dorsolateral prefrontal circuit function
responsible for planning, problem solving and working memory
41
Syndromes of the dorsolateral circuit
Dysexecutive syndrome
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Syndromes of the medial frontal circuit
Amotivational syndrome
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Syndromes of the orbito frontal circuit
Disinhibition syndrome
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What is the most well-known portrait of brain injury related neurobehavioral syndromes in film and history?
Apathy syndrome
45
Apathy Syndrome symptoms
absence of motor or psychic initiative indifference to pain, thirst, hunger Lack of spontaneous movement/speech Lack of desire Flat affect Apathy \< Abulia \< Akinetic Mutism
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Abulia definition
an absence of willpower or an inability to act decisively, as a symptom of mental illness.
47
apathy definition
lack of interest, enthusiasm, or concern
48
Akinetic mutism definition
Akinetic mutism is a medical term describing patients tending neither to move (akinesia) nor speak (mutism). Akinetic mutism was first described in 1941 as a mental state where patients lack the ability to move or speak. However, their eyes may follow their observer or be diverted by sound.
49
Identify
50
apathy syndrome circuit effected
Medial Frontal
51
Disinhibition syndrome symptoms 7 listed
* Lack of social tact/comportment * inappropriately jocular/sexual/antisocial * Inattentive/distractible/hyperkinetic * Disinhibition * Lack of judgment * Lack of responsibility * Imitation/utilization
52
Disinhibition Syndrome tests
53
WTF is this?
54
Dysexecutive syndrome symptoms 6 listed
* Poor visual/spatial/motor organization/strategy * Difficulty shifting/maintaining set * Reduced verbal/design fluency * Poor focus/inattention * Poor hypothesis generation * Poor memory search/retrieval
55
Dysexecutive syndrome tests
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Dorsolateral syndrome symptoms 5 listed
57
Dorsolateral circuit syndrome AKA
Dysexecutive syndrome
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Focal treatment for frontal lobe syndromes
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TMS for depression
60
What is this?
61
Summary: explain medial frontal orbito frontal dorsolateral frontal
62
Conclusions of the frontal lobes