Opthalmics Flashcards Preview

Pharmaceutics Spring 2016 > Opthalmics > Flashcards

Flashcards in Opthalmics Deck (20)
1

T/F?
NON-STERILE products are used for instillation of the eye.

False
STERILE

2

Name the 4 types of sterile products intended for instillation into the eye?

-Solutions
-Suspension
-Ointments
-Ophthalmic inserts

3

What are the 5 drug classes used in the eye?

-anti-inflammatory
-antibiotic
-vasoconstrictors
-miotics
-mydriatics

4

What parts of the eye are considered transparent media with no blood vessels? (3)

-cornea
-lens
-vitreous

5

How are oxygen and nutrients transported to non-vascular areas throughout the eye?

aqueous humor

6

Name the following volumes:
Tear Volume(eye moisture)-
How much volume can the eye hold-
Eye drop volume

Tear volume- 7 uL
Eye holds- 10 uL
Eye drop- 50-75 uL

7

Ophthalmic solutions are normally packaged in multiple dose containers that contain what?

preservatives

8

What are the 3 types of functional uses for contact lenses?

-corrective
-cosmetic
-therapeutic

9

What are the 3 types of lenses available?

-soft
-hard
-rigid gas permeable

10

Which type of lenses uses a hydrogel such as (HEMA- hydroxytethyl methacrylate)?

Soft lenses

11

Transscleral iontophoresis is used under what circumstances?

for drug targeting to posterior segment of eye

12

What are the 2 type of contact lens solution?

-Multi-purpose: rinsing and storage agent
-Enzymatic cleaning, disinfection, and neutralization

13

vasoconstrictors?

remove redness in the eye (should not be used chronically)

14

miotics?

constrict the pupil

15

mydriatics?

dilate the pupil--> to see the back of the eye

16

An eye drop contains 50-75 uL, although the eye can only hold 10uL. Where does the extra volume go?

drained off by nasolacrimal drainage (nose and throat)

17

What is the purpose of increasing the viscosity?

to increase how long the contact is in contact with the eye

18

_____ drugs are better absorbed in the body

unionized

19

Of the products used for instillation which has the highest increased contact time?

ophthalmic inserts

20

What has allowed extended wear of contact lenses due to high oxygen permeability?

silicone hydrogel