Capsules Flashcards
(16 cards)
Advantages of solid dosage (5)
- convenient
- light weight
- tasteless
- easy identification
- long shelf life
T/F Capsules almost always have an excipient
TRUE
______ is what makes opaque color
titanium dioxide
Capsules can be found in ____ or ____ gelatin shell
soft or hard (both contain 12-16% water)
How is gelatin obtained?
by partial hydrolysis of collagen (from skin and bones of animals)
T/F gelatin is soluble in hot water and warm gastric fluid
TRUE
Do companies marketing capsule products make the capsule shells first or are they made as part of the filling process?
the capsule shells are made first
__________ is very important when making the capsule shells
controlled temperature
How are the 2 capsule parts brought together?
- sealed by colored bands of gelatin
- locking groves in the shell wall
000 and 5, which is larger?
000 is the largest–> the larger the number the smaller the capsule
In order to determine if a formulation will fit in a capsule?
you need the bulk density of the formulation
What 3 things help with the flow rate of capsules?
- diluent
- glidant
- lubricant
magnesium stearate is an example of?
lubricant–> it is hydrophobic
What is the goal of mixing and blending of capsules?
to produce a homogeneous mass
What is the purpose of making 5-10% extra powder?When is this not okay?
some may be lost; when making control substances
rotary die process
liquid gelatin formed into two continuous ribbons
