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Pharmaceutics Spring 2016 > Capsules > Flashcards

Flashcards in Capsules Deck (16)
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1

Advantages of solid dosage (5)

-convenient
-light weight
-tasteless
-easy identification
-long shelf life

2

T/F Capsules almost always have an excipient

TRUE

3

______ is what makes opaque color

titanium dioxide

4

Capsules can be found in ____ or ____ gelatin shell

soft or hard (both contain 12-16% water)

5

How is gelatin obtained?

by partial hydrolysis of collagen (from skin and bones of animals)

6

T/F gelatin is soluble in hot water and warm gastric fluid

TRUE

7

Do companies marketing capsule products make the capsule shells first or are they made as part of the filling process?

the capsule shells are made first

8

__________ is very important when making the capsule shells

controlled temperature

9

How are the 2 capsule parts brought together?

-sealed by colored bands of gelatin
-locking groves in the shell wall

10

000 and 5, which is larger?

000 is the largest--> the larger the number the smaller the capsule

11

In order to determine if a formulation will fit in a capsule?

you need the bulk density of the formulation

12

What 3 things help with the flow rate of capsules?

-diluent
-glidant
-lubricant

13

magnesium stearate is an example of?

lubricant--> it is hydrophobic

14

What is the goal of mixing and blending of capsules?

to produce a homogeneous mass

15

What is the purpose of making 5-10% extra powder?When is this not okay?

some may be lost; when making control substances

16

rotary die process

liquid gelatin formed into two continuous ribbons