orthopaedic oncology Flashcards

1
Q

what does osteo mean?

A

bone

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2
Q

what does chondro mean?

A

cartilage

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3
Q

what does sarco mean?

A

soft tissue

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4
Q

what does sarcoma suggest?

A

malignancy of bone/soft tissue

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5
Q

most common place for metastases?

A

breast, lung, prostate, renal (kidney) , thyroid

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6
Q

3 most common sarcomas?

A
  1. Ostesarcoma
  2. Chondrosarcoma
  3. Ewing’s sarcoma
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7
Q

presenting features of bone cancer?

A
  • persistent, increasing pain
  • worse at night
  • swelling and erythema over joint
  • palpable mass
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8
Q

where does osteosarcoma usually present?

A

usually around distal femur/ proximal tibia

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9
Q

who does osteosarcoma usually affect?

A

children/young adults

2nd peak in elderly

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10
Q

what is the treatment for osteosarcoma?

A

chemotherapy and limb salvage

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11
Q

where do osteosarcomas usually metastasise to?

A

pulmonary

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12
Q

what age is usually affected by Ewings sarcoma?

A

young people (5-25)

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13
Q

where is Ewing’s sarcoma usually found?

A

diaphysis of long bones usually in distal femur/proximal tibia

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14
Q

what is the treatment for ewings sarcoma?

A

chemotherapy with limb salvage +/- adjuvant radiation

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15
Q

what is the treatment for ewigns sarcoma?

A

chemotherapy with limb salvage +/- adjuvant radiation

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16
Q

who does chondrosarcoma usually affect?

A

older patients 40-75 years

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17
Q

where are chondrosarcomas usually found?

A

pelvis, proximal and distal femur

18
Q

is osteoid osteoma benign or malignant?

A

benign

19
Q

what does osteoid osteoma look like on an Xray?

A

like a little O

20
Q

who usually is affected by osteoid osteoma?

A

young people aged 5-25

21
Q

where are osteoid osteomas usually found?

A

in the long bones

22
Q

how does an osteoid osteoma usually present?

A

-pain which is worse at night but can be controlled by aspirin

23
Q

what is the treatment for an osteoid osteoma?

A

can resolve spontaneously or with radiofrequency ablation

24
Q

how would an osteoid osteoma be described on xray?

A

as a little O

-central nodule of woven bone with osteblastic rim

25
Q

what is the commonest benign bone tumour?

A

osteochondroma

26
Q

what age is usually affected by osteochondromas?

A

adolescents/young adults

27
Q

who does enchondroma usually affect?

A

20-50 year olds

28
Q

how does enchondroma present?

A

usually asymptomatic

29
Q

what is an enchondroma?

A

benign intrmedullary cartilage lesion

30
Q

what is the treatment for enchondroma?

A

conservative treatment, curettage and bone grafting if symptomatic

31
Q

what is the treatment for enchondroma?

A

conservative treatment, curettage and bone grafting if symptomatic

32
Q

what is an osteosarcoma?

A

a malignant bone tumour that produces bone

33
Q

what causes an osteosarcoma?

A

mutation in the retinoblastoma gene

34
Q

osteosarcoma presenting symptoms?

A
  • constant pain
  • weight loss
  • worse at night
  • fatigue
35
Q

what is chondrosarcoma?

A

a malignant cartilage producing primary bone tumour

36
Q

what causes a chondrosarcoma?

A

unknown

37
Q

how does a chondrosarcoma present?

A
  • back or thigh pain
  • sciatica
  • bladder pain
  • unilateral oedema
38
Q

what is the treatment for chondrosarcoma?

A

SURGERYYY

-no chemo or radiotherapy :(

39
Q

how would you describe the way in which you chondrosarcomas metastases?

A

large and slow to metastases

40
Q

how would you describe Ewing’s sarcoma?

A

small round blue cell tumour