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Flashcards in Oxidative Phosphorylation Deck (81)
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61

in mitchells loops, 2 protons are moving  ___. this is driven by ___. 

against the gradient

driven by redux reactions

62

stoichimotery of mithcells loops? 

2H+/e- or 4H+/2 e-.

63

On the inside surface, an iron-sulfur center of a dehydrogenase and Cyt bh donate 1 e- each to___

 Q

64

 Q must also pick up ___ from the aqueous inside phase 

after getiting electron from  iron-sulfur center of a dehydrogenase and Cyt bh 

2 H+ 

65

after Q picks up 2 electrons and 2 ptorons it then must ___ to be oxidized

diffuse outside surface to be oxidize

66

after QH2 2 electorn complex diffuses to outside surface what happens?

1 electron is rtansferred to iron sulfur center and another to cyt b

67

once Q gets rid of its electrons..

loses both hydrogens to become fully oxidized

then diffuses back inside to begin next cycle

68

a hydrogen acceptor (i.e., H+ + e-) such as Q is reduced on the inside surface of the inner mitochondrial membrane by electron donors that can supply

 electrons but not the required protons

protons are received from the matrix

69

once Q is reduced, the hydrogen donor can move to be

oxidized

70

where does Q dump the protons?

in the intermembrane space 

71

explain the rotatry wheel of atp synthease

A H+ enters a channel and hops on to c subunit

c subunit rorates until the proton is aligned with a second channel

3. c rotary wheel is anchored to γ, when c subunits rotate realtive to a, γ is forced to rotate relative to the catlaytic subunits

4. the drive is protons moving down gradient is coupled with need to break atp off, allowing atp to be broken off

72

The ___synthase is now recognized to be a tiny molecular motor.

FoF1-ATP 

73

what are the only known proton driven rotary motor 

- bacterial flagella motor

- FoF1-ATP synthase

74

with Glycerol phosphate shuttle you only get ___ atp

2 atp/2 e

75

why do you only get 2 atp with Glycerol phosphate shuttle

Doesn’t involve membrane transport since the mitochondrial glycerol-phosphate dehydrogenase is on the outside surface of the inner membrane.

 

just goes to complexes 2 and 3

76

 Malate/aspartate shuttle gives ____ atp

3 atp/2e

77

 Malate/aspartate shuttle (~3 ATP/2 e-) present in___

 liver and heart

78

Glycerol phosphate shuttle (~2 ATP/2 e-), present in 

some muscle and nerve cells.

79

adp/atp trnsslocator is ___

electrogenic

bc you are eliminating one of the positive charges

80

One P - and one H+ move in trnaslocator results in 

 a net loss of one H+ from the concentration gradient i
but with no change in charge (electroneutral).

81

what are the roles of H gradient?