Patho week 3 lecture quiz Flashcards

1
Q
  1. Histamine is the most important mediator in Type I Hypersensitivity causes all of the following except:
A

increased cardiac contractility, which results in hypertension

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2
Q
  1. The coagulation Factors II, VII, IX, X, protein C, and S are dependent on ______ for their synthesis.
A

Vitamin K

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2
Q
  1. Allergic (extrinsic) asthma is associated with
A

IgE mediated airway inflammation

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3
Q
  1. The major cause of death from leukemic disease is
A

infection

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4
Q
  1. RhoGAM (an Rh antibody) would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.
A

negative, unsensitized, negative, positive

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5
Q
  1. Which condition is associated with an elevated reticulocyte count?
A

Hemolytic Anemia

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6
Q
  1. A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia?
A

Iron Deficiency Anemia

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7
Q
  1. Clinical manifestations of chronic arterial obstruction include
A

intermittent claudication

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7
Q
  1. While in the hospital for management of acute lymphoid leukemia (ALL), a patient develops severe thrombocytopenia. The most appropriate action for this condition is
A

activity restriction or platelet transfusion

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7
Q
  1. Treatment for hemophilia A includes
A

factor VIII replacement

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8
Q
  1. What laboratory finding is usually found in aplastic anemia?
A

Pancytopenia (low RBC, WBC & platelet count)

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9
Q
  1. Risk factors for atherosclerosis include which one?
A

non-modifiable: Age gender and family hx
modifiable: diet, exercise, smoking, stress, hypertension, hyperlipidemia, obesity & inflammation,

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10
Q
  1. Blood flow throughout the periphery is regulated by
A

the autonomic nervous system

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10
Q
  1. Which is false about the stages of Hemostasis?
A
  1. Vasoconstriction 2. Platelet plug formation 3. Coagulation (clot formation)
  2. Clot retraction/repair 5. Fibrinolysis (clot dissolution)
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10
Q
  1. Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are obstruction of the superior vena cava and compression of the
A

spinal cord.

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11
Q
  1. Which viruses have been implicated as cancer-causing agents? (Select all that apply.)
A

-Epstein-Barr
- Human T-cell leukemia
- Human immunodeficiency
………………………………….
HPV, HBV, HCV,

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11
Q
  1. Which causes vasoconstriction?
A

Norepinephrine

11
Q
  1. What is involved in the release of plasminogen activators? (Select all that apply.)
A

Factor XII, HMWK (High Molecular Weight Kininogen), Kallikrein and Thrombin

11
Q
  1. Which diseases may be associated with a bleeding problem? (Select all that apply.)
A

Renal Failure
Liver Cirrhosis
Systemic Lupus Erythematous
Ovarian CA

12
Q
  1. A deficiency of von Willebrand factor impairs
A

platelet adhesion to injured tissue

12
Q
  1. Hemophilia B is also known as
A

Christmas disease.

12
Q
  1. Which clinical finding is indicative of compartment syndrome?
A

Absent peripheral pulses

13
Q
  1. When systemic vascular resistance is decreased, blood flow
14
Q
  1. When a patient is struck in the eye by a baseball, the result is redness and swelling. This increase in blood flow to a localized area is called
15
25. The pain characteristics of chronic venous insufficiency include (Select all that apply.)
-aching and cramping in the affected area. -relief with elevation to the area. -relief with ambulation if pain is in the legs
16
26. Venules are composed of _______ tissue.
connective
17
Which will not belong to the category of Myeloid neoplasms?
-Acute Lymphoblastic Leukemia (ALL) -Chronic Lymphocytic Leukemia (CLL) -Lymphomas
17
Thalassemia may be confused with iron-deficiency anemia, because they are both
microcytic
18
27. This disease affects the neuromuscular junction: primarily the acetylcholine receptor (AChR) and is an example of type II hypersensitivity, reactions.
Myasthenia Gravis
19
31. A serious complication of deep vein thrombosis is
pulmonary embolus
19
Anaphylaxis may occur in certain hypersensitivity reactions, including type (Select all that apply.)
Type I & Type II
20
Which is not considered to be a risk factor for thrombus formation?
Thrombocytopenia
20
38. The red blood cells produce energy (ATP) by___________ (select all that apply)
- Glycolysis - Lactic Acid Fermentation
21
35. One of the cardinal features of sickle cell anemia includes acute and chronic dysfunction of which organs? (Select all that apply.)
-spleen -bones -brain -lungs
21
36. In a mature red blood cell, the hemoglobin is composed by ____ percentage of the cell's dry weight.
95%
21
33. Which condition is associated with an elevated reticulocyte count?
Hemolytic Anemia
21
37. After dietary iron is absorbed in the small intestine, it is transported in the blood by protein called
transferrin.
21
34. Red blood cells obtain nearly all their energy from metabolism of
glucose
21
39. Erythropoiesis cannot proceed without which of the following vitamins/nutrients? (select all that apply)
-Iron -Folate -Vitamin B12 -Vitamin C
22
40. Which is false about Hereditary Spherocytosis?
False: Hereditary Spherocytosis has a decreased osmotic fragility test True: -Hereditary Spherocytosis is an Inherited, Autosomal Dominant disease. -Hereditary Spherocytosis is caused by a Deficiency in Spectrin which comprises the Red Cell Membrane, resulting in a Spherocyte shape. -Hereditary Spherocytosis results in Extravascular Hemolysis in the Spleen. -Hereditary Spherocytosis affects Northern Europeans through Autosomal Dominant inheritance. - Childhood will exhibit Anemia, Splenomegaly, and Jaundice. - Adulthood may exhibit Gallstones