Pharm 1 - Exam 1: Cardio/Resp Flashcards Preview

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Flashcards in Pharm 1 - Exam 1: Cardio/Resp Deck (85)
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31

Which of the diuretics is most likely to cause hypercalcemia?

Hydrochlorthiazide/Hydrodiuril

32

What is a common dose of K+ given to patients on K+ wasting diuretics?

10mE or 750mg KCl

33

Which diuretic is K+ sparing?

Spironolactone/Aldactone

34

Which diuretic is a direct aldosterone antagonist?

Spironolactone/Aldactone

35

Do not use this diuretic for pts taking K supplements, ACE inhibitors or ARBs OR those with renal insufficiency, uncontrolled DM or osteomyelitis.

Spironolactone/Aldactone

36

This K+ sparing diuretic is a Na+ channel blocker

Triamterene/Dyrenium

37

Where are the highest concentration of Beta 1 and Beta 2 receptors?

B1: heart
B2: lung

38

What is the antidote to b-blockers? MOA?

glucagon
increase cAMP in myocardium, bypasses beta adrenergic 2nd messenger system

39

Which patients should not be given Propanolol/Inderal?

COPD/asthma (it is known to cause bronchospasm)
cardiac conduction abnormalities

40

What class of drugs may result in rebound tachycardia, HTN, stroke of MI if discontinued suddenly?

beta blockers

41

Name 3 Category X drugs

Lisinopril (ACE inhibitor)
Warfarin (anticoagulant)
Lorsartan (angiotensin II receptor blocker)

42

This drug is a cardiac specific beta 1 blocker

atenolol/tenormin

43

This class of drugs is known to cause weakness, fatigue, lethargy, depression, CNS disturbance, sexual dysfunction, bradycardia

beta blockers

44

What three conditions in addition to HTN would lead someone to use a beta blocker as a first line therapy?

migraine
angina
MI soothed by beta blockers previously

45

Which of the alpha blockers blocks alpha 1 receptors?

Prazosin/Minipress

46

What is the MOA of Rauwolfia Alkaloids/Reserpine?

Peripheral adrenergic blockade

47

Name the Ca Channel Blocker

Verapamil/Isopten

48

What drug is most indicated for treating vasospastic angina in addition to HTN?

Verapamil/Isopten

49

What is the risk of using Ca Channel Blockers with beta blockers?

bradycardia

50

What is the drug of choice in treating pts with HTN and DM? What is its class?

Lisinopril/Prinivil (ACE inhibitor)

51

Which drug inhibits the degradation of bradykinins, resulting in a dry irritating cough?

Lisinopril/Prinivil

52

Someone comes in with angioedema. What drug might they be taking?

Lisinopril/Prinivil

53

What class of drugs should Lisinopril never be mixed with?

K+ sparing diuretics. It has a potential for hyperkalemia on its own

54

What is the drug of choice in treating HTN with CHF of DM in conjunction with proteinuria? What is it's class?

Losartan/Cozaar (ARB)

55

What is the MOA for Losrtan/Cozaar (ARB)?

blocks the effects of angiotensin II, decreasing peripheral vasoconstriction.

56

This drug does not block the degredation of bradykinins and therefore produces less of a cough compared to ACE inhibitors

Losartan/Cozaar (ARB)

57

This drug reduces peripheral sympathetic nervous activity by stimulating the presynaptic alpha2 adrenergic receptors in the CNS.

Methyldopa/Aldomet

58

What drug might you use when a pt's HTN does not respond to 2-3 meds concurrently?

Methyldopa/Aldomet

59

In what class of drug is Methyldopa/Aldomet?

Centrally Acting Alpha Agonist

60

Name 2 direct vasodilators and their most notable side effects.

Minoxidil/Loniten (hirsuitism) AKA Rogaine
Hydrakazine/Apresoline (Drug-induced SLE)