Flashcards in Pharm 1 - Exam 1: Cardio/Resp Deck (85)
Which of the diuretics is most likely to cause hypercalcemia?
What is a common dose of K+ given to patients on K+ wasting diuretics?
10mE or 750mg KCl
Which diuretic is K+ sparing?
Which diuretic is a direct aldosterone antagonist?
Do not use this diuretic for pts taking K supplements, ACE inhibitors or ARBs OR those with renal insufficiency, uncontrolled DM or osteomyelitis.
This K+ sparing diuretic is a Na+ channel blocker
Where are the highest concentration of Beta 1 and Beta 2 receptors?
What is the antidote to b-blockers? MOA?
increase cAMP in myocardium, bypasses beta adrenergic 2nd messenger system
Which patients should not be given Propanolol/Inderal?
COPD/asthma (it is known to cause bronchospasm)
cardiac conduction abnormalities
What class of drugs may result in rebound tachycardia, HTN, stroke of MI if discontinued suddenly?
Name 3 Category X drugs
Lisinopril (ACE inhibitor)
Lorsartan (angiotensin II receptor blocker)
This drug is a cardiac specific beta 1 blocker
This class of drugs is known to cause weakness, fatigue, lethargy, depression, CNS disturbance, sexual dysfunction, bradycardia
What three conditions in addition to HTN would lead someone to use a beta blocker as a first line therapy?
MI soothed by beta blockers previously
Which of the alpha blockers blocks alpha 1 receptors?
What is the MOA of Rauwolfia Alkaloids/Reserpine?
Peripheral adrenergic blockade
Name the Ca Channel Blocker
What drug is most indicated for treating vasospastic angina in addition to HTN?
What is the risk of using Ca Channel Blockers with beta blockers?
What is the drug of choice in treating pts with HTN and DM? What is its class?
Lisinopril/Prinivil (ACE inhibitor)
Which drug inhibits the degradation of bradykinins, resulting in a dry irritating cough?
Someone comes in with angioedema. What drug might they be taking?
What class of drugs should Lisinopril never be mixed with?
K+ sparing diuretics. It has a potential for hyperkalemia on its own
What is the drug of choice in treating HTN with CHF of DM in conjunction with proteinuria? What is it's class?
What is the MOA for Losrtan/Cozaar (ARB)?
blocks the effects of angiotensin II, decreasing peripheral vasoconstriction.
This drug does not block the degredation of bradykinins and therefore produces less of a cough compared to ACE inhibitors
This drug reduces peripheral sympathetic nervous activity by stimulating the presynaptic alpha2 adrenergic receptors in the CNS.
What drug might you use when a pt's HTN does not respond to 2-3 meds concurrently?
In what class of drug is Methyldopa/Aldomet?
Centrally Acting Alpha Agonist