Pharm 1 - Exam 1: Cardio/Resp Flashcards Preview

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Flashcards in Pharm 1 - Exam 1: Cardio/Resp Deck (85)
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61

What drug falls in the category of renin-blocker?

Aliskiren/Tekturna

62

What is the MOA of IV Nitroglycerine and IV Sodium Nitroprusside and when might you use them?

NO = vasodilation of veins and arteries
Emergency anti-HTN

63

A woman comes in with emergent pregnancy-induced HTN, what drug would be used?

IV Labetalol

64

What is the MOA for aspirin?

irreversibly inhibits COX 1 and 2 = decrease platelet agg.

65

Someone comes in with hyperventilation, tinnitis, dizziness, n/v. What is this constellation of symptoms called when associated with aspirin?

Salicylism

66

In what patients is aspirin indicated to reduce MI?

unstable angina
hx of infarction

67

This drug is an ADP receptor antagonist and is known to reduce the risk of thrombotic events

Clopidogrel/Plavix

68

This anti-thrombotic drug is CI in pts with internal bleeding, intracranial hemorrhage, head trauma, or stroke w/i 30 days

Abciximab/Reopro

69

What class of drug is Abciximab/Reopro?

Glycoprotein IIB/IIIA inhibitor

70

These three anti-coagulants inactivate factor X(Xa)

Heparin
Enoxaparin/Lovenox (LMW Heparin)
Rivatoxaban/Xarelto

71

What is the most unique side effect of Enoxaparin?

Heparin induced throbocytopenia (HIT) syndrome
discontinue if platelets drop below 100,000/mm3

72

Protamine sulfate antidotes what drugs?

Heparin, Enoxaparin/Lovenox (LMW Heparin)

73

This anticoagulant affects vitamin K dependent factors

Warfarin/Coumadin

74

This is the only drug that actually lyses clots via the activation of plasmin.

Streptokinase

75

What drug should not be given to pts who have had reent head trauma, GI bleed, surgery or intracranial neoplasm within the last 30 days?

Streptokinase

76

Which drugs should not be prescribed with Silendafil/Viagra?

Nitrates (nitroglycerin and Isosorbide Dinitrate/Isordil)

77

This is a long acting nitrate vasodilator

Isosorbide Dinitrate/Isordil

78

Beta blockers are mainly indicated in what conditions?

HTN
Angina
post-MI
Panic-attacks

79

What is the antidote for Amlodopine/Norvasc (a Ca+ Channel Blocker)?

Calcium gluconate

80

What drug might be used for pain relief in unstable angina?

morphine (opiate receptor agonist)

81

For what is Nalaxone/Narcan an antidote?

Morphine

82

What is the acronym for unstable angina?

M: morphine
O: oxygen
A: aspirin
N: Nitroglycerin

83

What is the antidote for Streptokinase?

Aminocapoic Acid

84

What drug is particularly indicated for HTN and BPH?

Prazosin/minipress

85

Which drug is CI for those with sulfa allergies?

HCTZ