Practice Question Note Cards Flashcards Preview

BMS > Practice Question Note Cards > Flashcards

Flashcards in Practice Question Note Cards Deck (48):
1

Occurs when one allele of a gene is transcribed. This occurs during genomic imprinting in which either paternal or maternal gene is expressed, but not both

Monoallelic expression

2

Zinc atoms associate with domains of steroid receptor protein domains to form zinc finger that

Bind DNA

3

Where do pKa's 1, 2, and 3 occur?

pKa 1: at 0.5 eq's of titrant
pKa 2: at 1.5 eq's of titrant
pKa 3: at 2.5 eq's of titrant

4

pKa's occur every

0.5 eq's of titrant added

5

Buffer regions are approximately

pKa +/- 1

6

TFIIH is a general transcription factor with

Helicase activity

7

The binding of a steroid hormone to its receptor causes a conformational change in the receptor that uncovers its

Zinc finger DNA binding domain

8

Plays several key roles in ribosomes, including: recognition and positioning of tRNA and mRNA and catalyzing peptidyl transferase activity of 60S subunit

rRNA

9

DNA molecules made as a copy of mRNA and therefore lacking the introns that are present in the genomic DNA

-used to determine amino acid sequence of a protein by DNA sequencing or to make the protein in large quantities by cloning followed by expression

Complimentary DNA (cDNA)

10

cDNA is used to determine the amino acid sequence of a protein by DNA sequencing or to make the protein in large quantities by

Cloning

11

Expression of a specific gene is down-regulated using RNA interference

Gene knockdown

12

Catalyze oxidation/reduction reactions

Oxidoreductases

13

Catalyze the transfer of C-, N-, or P- containing groups

Transferases

14

Catalyze the cleavage of bonds by addition of water

Hydrolases

15

Catalyze cleavage of C-C, C-S, and certain C-N bonds

Lyases

16

Catalyze racemization of optical or geometric isomers

Isomerases

17

Catalyze formation of bonds between carbon and O, S, and N coupled to hydrolysis of high energy phosphates

Ligases

18

According to the CDC, what immunization is indicated for a baby before the baby leaves the hospital?

Hepatitis B

19

For people with what condition is Zostavax contraindicated?

HIV Infection with CD4+ count

20

When do you have to have your meningococcal an Tdap (one each) immunizations by?

6th grade

21

How many doses of Hep B vaccine must you have by kindergarten-1st grade?

3

22

How many doses of polio vaccine must you have by the time you get to kindergarten-1st grade?

3 (one must be after 4th birthday)

23

Which vaccine requires 1 dose for children born after 1/1/97, given no earlier than ten years of age?

Meningococcal

24

What are the four main immunizations indicated for all adults

Influenza, Tdap, Varicella, MMR, Also potentially HPV

25

Vericella, Zoster, amd MMR are contraindicated for

1.) Pregnant women
2.) Immunocompromising condition (excluding HIV)
3.) HIV infected with CD4+ count

26

For women, one dose of Tdap is indicated for each

Pregnancy

27

Typically, we do not give babies MMR, Varicella, or Hep A shots until

12 months of age

28

What are the five vaccines we give babies at 2 months?

1.) Rotavirus
2.) DTap
3.) Hib
4.) Pneumococcal conjugate (PCV13)
5.) Polio (IPV)

29

Varicella, Zoster, and MMR are all

Live immunizations

30

The interval for PCV13 followed by PPSV23 has been changed from

6 months to 1 year

31

Meningitus B vaccine can be given to adolescents and young adults aged

16-23

32

What are the three principles of the characteristics of the disease?

1.) Significant morbidity and mortality
2.) Prolonged Asymptomatic Phase
3.) Effective treatment available?

33

What are the three principles of the characteristics of the population?

1.) High Prevalence
2.) Acceptance of the test
3.) Ability to comply/report

34

What are the three principles of the characteristics of the test?

1.) Sensitivity and Specificity
2.) Validity and Reliability
3.) Cost (effectiveness)

35

The reliability of mammography is not very

High

36

What is the sensitivity and specificity of the test for the prostate specific antigen (PSA)?

Sensitivity = 21%
Specificity = 91%

37

Which type of prostate cancer do we want to find?

Type B or C (but preferentially type B)

38

The prevalence of prostate cancer in 50 year olds is

50%

39

What is the cost per life saved?

$50, 000

40

Lipid screening for those without estrogen should begin at age

35

41

Lipid screening for everyone at risk for CAD should begin at age

20

42

What are four types of preventative services?

1.) Annual physicals
2.) Screening tests
3.) Immunizations
4.) Well-baby checkups

43

What are the immunizations required to attend NJ schools?

1.) DTap
2.) Polio
3.) MMR
4.) Hep B
5.) Varicella

44

What are four of the top ten causes of mortality?

1.) Cardiac
2.) Cancer
3.) COPD
4.) Accidents

45

The proportion of people in a population who have the disease at a particular point in time

Point Prevalence

46

The proportion of people who have the disease over a specified period of time.

Period Prevalence

47

The proportion of a population at risk that develops the disease (new cases) over a period of time.

Cumulative Incidence

48

The rate of new cases per the total amount of time people in the population were at risk, in this case measured as person-years. Incidence density is a measure of the incidence rate in a dynamic changing population, such as workers in a particular industry.

Incidence Density

Decks in BMS Class (62):