Protein and Amino Acid Metabolism I Flashcards
(45 cards)
what secretes HCl
parietal cells
what secretes pepsin
chief cells
endopeptidase
it cleaves internal peptide bons within proteins
what is the optimal pepsin activity pH
2
waht does secretin stimulate
acinar cells of pancreas to release HCO3- rich fluid
function of cholecystokinin
release of bile from gall bladder
release of digestive enzymes from pancrease
how does trypsinogen get converted to active trypsin
enteropeptidase
what is the liminal surface of epithelical cells of small intestine rich in
endopeptidase and aminopeptidase activity
waht are teh small neutral AA
gly, ser, ala
waht are teh alrge neurtral amino acids
leu, ile, phe, try, al, met, trp, gln
what are teh basic amino acids
arg, lys
what are teh acidic amino acids
asp, glu
what happesn when peptides get inside the epithelial cell
get rapidly hydrolysed by peptidases
how do free amino acids in epithhalial cells get to portal circualtion
facilitated diffusion into capillaries
how does hartnup disease work
blocks acitivty of AA transport that is responsible for uptake of large neutral amino acids
symptoms of hartnup disease
pellagra
how do you treat hartnup disease
niacin
what is celiac caused by
immune response to alpha-gliadin
how does nitrogen get into the body
dietary protein
how is nitrogen excreted
urea in urine
when would you get a negiatve nitrogen balance
not enough protein intake
when do you get a positive nitrogen balance
net increase in body protein (prengnat women, growing kids)
what does PvT Tim Hall stand for
pheny valine threonine tryptophan isoleucine methionine histidine arg leu lys
what is the is the essential AA for infants
arginine
