Flashcards in Pubertal Delay And Gonadal Dysgenesis Deck (9)
Delayed puberty (vs primary amenorrhea)? Most common cause?
No sexual secondary characteristics by age 14 (versus no menarche by age 16)
Gonadal dysgenesis – most commonly from Chromosome abnormality
Four stages of pubertal development?
Thelarche, pubarche/adrenarche, growth spurt, menarche
(boobs, pubes, growth, squirt)
Hypergonadotropic hypogonadism – Hormone levels? Most common cause? Other causes?
High FSH, low estrogen
Radiation, chemotherapy, inflammation, torsion
Patient Turner syndrome have what in place of ovaries?
Gonadal streak – fibrous band of tissues
When to remove gonads in patient with gonadal dysgenesis to avoid neoplastic changes?
Gonadal dysgenesis with 46, XY
Hypogonadotropic hypogonadism – hormone levels? Main cause? Other causes?
Low FSH, low estrogen
Hypothalamic defect (Eating disorders, chronic illness, extreme exercise)
Hypothyroidism, Cushing's, pituitary adenoma's, craniopharyngiomas
Hypogonadotrophic hypogonadism – most commonly associated neoplasm?
Management goals for patients with delayed puberty? Tx?
1. Initiate sexual maturation
2. Prevent osteoporosis (from hypoestrogenism Lumia)
3. Promote full height potential