Flashcards in Amenorrhea (Primary) Deck (12)
Definition of primary amenorrhea?
No menses by age 16
Most common causes of primary amenorrhea if normal breast development?
Mullerian agenesis and androgen insensitivity
Patient with primary amenorrhea and born with only one kidney – likely diagnosis?
Mullerian agenesis (significant fraction of these patients will have urinary tract abnormality)
Patient with primary amenorrhea and scant hair?
Patient with primary amenorrhea and absence of breast development?
Gonadal dysgenesis (turner syndrome)
46 XX female with congenital absence of uterus, cervix, and fallopian tubes? Do have what anatomical parts?
Mullerian agenesis; Ovaries (ovaries are not Mullerian structures)
Three most common causes of primary amenorrhea?
Pregnancy, androgen insensitivity, Mullerian agenesis
Differences: Mullerian agenesis versus androgen insensitivity? (3)
1. Normal hair versus absent hair
2. Normal testosterone versus high testosterone
3. XX versus XY
Complications of CAH? Prophylaxis? (When? Why then?)
Malignancy of intra-abdominal gonads
Gonadectomy after puberty (to allow for breast development and when you grow)
20-year-old patient with primary amenorrhea and Tanner stage one breast development – likely diagnosis? Complication?
Gonadal dysgenesis; gonadal malignancy
Teenage patient with absence of breast development and short stature – karyotype reveals 46 XX – diagnosis?
Gondal dysgenesis (can also happen in XY pt)