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Flashcards in Cervical Cancer Deck (18):
0

Most common presenting symptom of invasive cervical cancer?

Abnormal vaginal bleeding

1

Patient with cervical cancer – flank tenderness would indicate?

Metastatic obstruction of the ureter

2

Risk factors for cervical cancer?

Notably, this is not a risk factor?

1. early age of coitis or early childbearing (Early sex)
2. Multiple sexual partners (Lots of sex)
3. STIs, HPV, HIV (sex disease)
4. Cigarette smoking (post sex)
5. Low socioeconomic status

Family history is not a risk factor

3

Cervical intraepithelial neoplasia?

Preinvasive lesions of cervix with abnormal maturation, nuclear enlargement, and atypia

4

HPV – type of virus?

Circular, double-stranded DNA virus

8

Majority of cervical dysplasias/cancer arise where?

Squamocolumnar junction of the cervix

9

Ways to identify dysplastic lesions?

1. Acetowhite change after addition of acetic acid
2. Vascular pattern changes punctations, corkscrew vessels, hairpin vessels)

10

Patient presents with cervical mass – next step?

Biopsy

11

Staging procedure for cervical cancer?

1. Examination under anesthesia,
2. IV pyelogram
3. Chest radiograph
4. Barium enema or proctoscopy
5. Cystoscopy

12

Treatment of early versus advanced cervical cancer?

Radical hysterectomy or radiation

Versus

Radiotherapy (brachytherapy + teletherapy) + chemotherapy (cis-platinum)

13

Spread of cervical cancer? Can obstruct?

Through cardinal ligaments toward pelvic sidewalls; one or both ureters leading to hydronephrosis

14

Most common cause of death due to cervical cancer?

Bilateral ureteral obstruction

15

Cervical cytology is not recommended in women who have had? Exception?

Total hysterectomy for benign indications;

Annual Pap smear of vaginal cuff is still needed if hysterectomy is performed for cervical dysplasia

16

Patient with ASCUS, when to observe instead of immediate colposcopy?

Adolescents and pregnant patients

17

Advantages of hysterectomy over radiotherapy?

Preservation of sexual function and ovarian function (Vaginal agglutination is caused by radioactive implants, closing the vagina)

20

Radical hysterectomy?

Removal of the uterus, cervix, and supportive ligaments (cardinal, uterosacral) and proximal vaginia

21

Radiation brachytherapy versus radiation teletherapy?

Radioactive implants placed near tumor bed

versus

external beam radiation where target is

22

HPV vaccine covers what viruses?

6, 11, 16, 18

6 and 11 cause venereal warts; 16 and 18 are associated with cancer