Flashcards in Pulm Path I Deck (14)
What are the layers of the trachea from lumen out?
respiratory epithelium --> lamina propria --> submucosa --> tracheal cartilage
What type of epithelium comprises the primary bronchus?
pseudostratified columnar epithelium (nuclei at variable positions)
What comprises the upper airway?
nasal cavity, pharynx, larynx
What comprises the lower airway?
trachea, bronchi (at the bifurcation of the trachea)
Where does cartilage stop forming along the bronchopulmonary tree?
True or false: trachea is respiratory epithelium
true (goblet cells and cilia)
where is the conducting portion found?
main/primary and secondary/tertiary bronchi (similar structure to trachea)
Where are goblet cells replaced by Clara cells?
What are clara cells?
dome shaped cells without cilia and they secrete glycosaminoglycans and secretory proteins
what do bronchioles branch into?
tertiary bronchioles and then respiratory bronchioles (like alveoli)
What is the main histological difference between tertiary bronchus and bronchiole?
no cartilage in the bronchiole
clara cells in bronchiole
no goblet cells in bronchiole
What is the difference between the two types of alveolar epithelial cells?
type 1 = gas exchange, squamous
type 2 = secrete surfactant and differentiate into type 1 cells, granular
What are 4 cell types in alveoli?
1) alveolar macs
2) endothelial cells
3) connective tissue cells (fibroblasts)