Quiz 4 Study Guide: Lungs Flashcards Preview

Human Disease and Therapeutics > Quiz 4 Study Guide: Lungs > Flashcards

Flashcards in Quiz 4 Study Guide: Lungs Deck (41)
Loading flashcards...
1

What is Atelectasis?

Inadequate expansion of airspaces.

Some cause of aspiration, pneumothorax, and pleural fibrosis.

2

What is caused by trauma to the lung resulting in inflammation resulting in generalized fluid accumulation? (Progression of acute injury and damage from activated neutrophils)

***High Rate of Fatalities

Acute Respiratory Distress Syndrome (ARDS)

3

What are three components of COPD?

Emphysema, Asthma, and Bronchiectasis

4

What is Emphysema and what causes it?

Destruction of Alveolar walls and permanent enlargement of airspaces.

Smoking, Alpha-1 antitrypsin deficiency, air pollution

5

What is Chronic Bronchitis and what are its causes?

Persistent cough of 3 or more months in 2 consecutive years.

Smoking and air pollution

6

What is Bronchiectasis and what are its causes?

Obstruction of bronchi and persistent necrotizing infections.

Destruction of elastin and muscles in bronchial walls.

7

What is Asthma and what is it caused by?

Reactive airway disease and narrowing of airways (hyperactivity)

Hyperinflated lungs, thick mucus plugs in airways, smooth muscle hypertrophy.

8

What is Fibrosing Lung Disease?

Associated with collagen vascular diseases such as rheumatoid arthritis.

9

What is Occupational Lung Disease?

Restrictive

E.g. Mineral dust induced, silicosis, asbestosis (mesothelioma)

10

What is Sarcoidosis?

Restrictive disease (abnormal connective tissue and reduced elastic properties)

*** Multi-organ involvement

11

What are the two vascular diseases of the lung?

Pulmonary Embolus
Pulmonary Hypertension

12

What is a Pulmonary Embolus?

A vascular disease of the lung that can cause sudden death if in the pulmonary artery. It originates from deep veins in the legs.

13

What is Pulmonary Hypertension?

Causes Heart Disease and recurrent Thromboemboli.

***Cor Pulmonale***

14

What is Cor Pulmonale?

Right Ventricular Failure

15

What are the 3 types of lung disease?

Restrictive
Vascular
Obstruction

16

What are characteristics of a Restrictive Lung Disease?

Caused by fibrosis or chest wall abnormalities
Gas exchange is impaired
Difficulty inhaling and expanding lungs

17

What are characteristics of a Vascular Lung Disease?

Gas exchange impaired by obstruction or hemmorage
May be abrupt or insidious

18

What are characteristics of a Obstructive Lung disease?

Blocked airways
Gas exchange through septal walls not impaired
Unable to exhale

19

What is the cause of Tuberculosis?

Mycobacterium Tuberculosis

20

What are characteristics of Tuberculosis?

-Usually in the Lungs but can affect other organs
-Flourishes in crowded impoverished areas
-Non-Contagious during long periods of dormancy
-Problems with multi drug antibiotic resistance
-Froms Necrotizing Granulomas


21

95% of Lung tumors are...

Carcinomas
(adeno and squamous cell types most common)

22

What population is 55X more likely to develop Lung tumors?

Smokers

23

In what populations is Asthma the most prevalent?

Children and females

24

What are the seven different types of asthma medication?

Relievers
Controllers
Add-on Controllers
Antimuscarinics
Leukotriene Modifiers
Cromolyn
Omalizumab

25

What are characteristics of Relievers?

-Short Acting
-Less Severe Cases
-Typically Beta 2 agonist

26

What two Beta 2 agonists are used as Relievers for asthma?

Albuterol: 4-6 Hour effect; Rapid onset
Salmetrol: 12 Hour effect; Slower onset

27

What is the Mechanism of Action of Relievers?

Directly relax airway smooth muscle.

28

What are the characteristics of controllers

Need to be taken long term for stable control (more side effects)

Normally inhaled (Corticosteroids, etc for moderate to severe asthma.

***Often combine with B2 agonist
***Chronic Management, not rescue
*** e.g. Fluticasone

29

What are side effects of controllers?

Nose bleeds
Sores that don't heal on the nose, tongue and mouth

30

What are add on controllers?

Methyxanthine drugs
Theophylline (tablet or inhaler)