quiz 7 Flashcards

1
Q

what are the 4 dietary lipids?

A

TAG
FSV
Cholesterol and CEs
phospholipids (PL)

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2
Q

describe TAG digestion in the stomach

A

TAG clumps together in the stomach and the exterior is digested by gastric lipase.
it removes one FA to create DAG.

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3
Q

describe TAG digestion in the small intestine

A

cck is secreted when chyme enters
the pancrease releases pancreatic lipase and colipase, which acts on the gallbladder to secrete bile

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4
Q

what are the lipids broken down into

A

emulsification droplets

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5
Q

describe emulsification droplets

A

lipids make up the center and bile salts make up the exterior

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6
Q

what binds to the droplet? why

A

pancreatic colipase, so lipase can access the lipids

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7
Q

what does pancreatic lipase remove

A

2 FAs from TAG and 1 FA from DAG

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8
Q

what is the end product of TAG digestion

A

MAGs and FAs, which need to get absorbed

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9
Q

what do droplets become after absorption

A

bile salts micelles

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10
Q

how are the products of digestion transported to the ER

A

fatty acid binding proteins

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11
Q

define reesterification

A

fatty acids recombining with MAGs

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12
Q

describe chylomicrons

A

what TAGs are packaged in
help with lipid transport

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13
Q

where do lipids first enter after the small intestine?

A

the lymphatic system

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14
Q

what are TAGs broken down to in the ruminant

A

1 glycerol and 3 FAs

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15
Q

what is glycerol converted to

A

VFAs

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16
Q

why is too much fat a problem

A

it can be toxic to animals

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17
Q

why are PUFAs more toxic

A

they contain double bonds

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18
Q

define bihydrogenation

A

removes double bonds in PUFAs

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19
Q

FAs can/can not cross the brush border

A

can

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20
Q

can lipid transport freely occur?

A

no

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21
Q

describe very low density lipoproteins

A

instead of going to the lymphatic system, it goes to the liver

22
Q

what makes up density

A

lipid:protein

23
Q

define apolipoproteins

A

proteins associated with lipoproteins

24
Q

what are the functions of lipoproteins

A

structural, cofactor for enzymes, and/or ligands for receptors

25
what does apoB100 do
acts as a ligand
26
what does apoE do
acts as a structure and cofactor
27
what does apoC2 do
acts as a cofactor
28
what does chylomicron contain
apoB48
29
what does chylomicron react with in the bloodstream
apoC2
30
what does chylomicron do
binds to enzymes in the capillary walls and releases lipids
31
what is chylomicron a cofactor for
lipoprotein lipase
32
what are lipoprotein lipases broken down into
glycerol and FAs
33
where does glycerol go
the liver
34
where do FAs go
into tissue for energy or storage
35
what happens when 80% of the TAGs are released
apoC2 dissociates from chylomicrons
36
define chylomicron remnant
what remains when apoC2 dissociates from chylomicrons
37
when does chylomicron remnant get removed from the bloodstream
when apoB48 binds to the receptor on liver cells
38
what do VLDLs use
apoB100 and apoE
39
what do VLDLs associate with in the bloodstream
apoC2
40
how many TAGs are initially released with VLDLs
50%
41
what is created when apoC2 is dissociated from VLDL
intermediate density lipoprotein
42
what do IDLs become
LDLs
43
what does LDL transfer
cholesterol from the liver into the body
44
what do LDLs use for transferring
apoB100
45
describe the LDL steps
travels through the bloodstream binds to apoB100 on capillary walls cholesterol is diffused into tissues
46
how long to LDLs stay in circulation
2 days
47
where do LDLs go when cholesterol is absorbed
back to the liver
48
what do HDLs do
the reverse of cholesterol transport: transport cholesterol from tissue using apoA1
49
what are the steps of HDLs
binds to apoA1 receptors on capillary walls cholesterol is desorbed from tissue returns to liver with cholesterol
50
what are the 4 roles of lipid metabolism
energy source structural components lubricants signaling molecules
51
what are the only two places that synthesize fat
adipose tissue and the liver