Rapid Review - Classic Labs / Findings (1) Flashcards Preview

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Flashcards in Rapid Review - Classic Labs / Findings (1) Deck (30):
1

Anticentromere antibodies

Scleroderma (CREST)

2

Antidesmoglein (epithelial) antibodies

Pemphigus vulgaris (blistering)

3

Anti–glomerular basement membrane antibodies

Goodpasture syndrome (glomerulonephritis and hemoptysis)

4

Antihistone antibodies

Drug-induced SLE (hydralazine, INH, phenytoin, procainamide)

5

Anti-IgG antibodies

Rheumatoid arthritis (systemic inflammation, joint pannus, boutonnière deformity)

6

Antimitochondrial antibodies (AMAs)

1° biliary cirrhosis (female, cholestasis, portal hypertension)

7

Antineutrophil cytoplasmic antibodies (ANCAs)

Microscopic polyangiitis and Churg-Strauss syndrome (MPO-ANCA/p-ANCA); granulomatosis with polyangiitis (Wegener; PR3-ANCA/c-ANCA)

8

Antinuclear antibodies (ANAs: anti-Smith and anti-dsDNA)

SLE (type III hypersensitivity)

9

Antiplatelet antibodies

Idiopathic thrombocytopenic purpura

10

Anti-topoisomerase antibodies

Diffuse systemic scleroderma

11

Anti-transglutaminase/anti-gliadin/anti-endomysial antibodies

Celiac disease (diarrhea, distention, weight loss)

12

“Apple core” lesion on abdominal x-ray

Colorectal cancer (usually left-sided)

13

Azurophilic peroxidase (+) granular inclusions in granulocytes and myeloblasts

Auer rods (AML, especially the promyelocytic [M3] type)

14

Bacitracin response

Sensitive: Streptococcus pyogenes (group A); resistant: Streptococcus agalactiae (group B)

15

“Bamboo spine” on x-ray

Ankylosing spondylitis (chronic inflammatory arthritis: HLA-B27)

16

Basophilic nuclear remnants in RBCs

Howell-Jolly bodies (due to splenectomy or nonfunctional spleen)

17

Basophilic stippling of RBCs

Lead poisoning or sideroblastic anemia

18

Bloody tap on LP

Subarachnoid hemorrhage

19

“Boot-shaped” heart on x-ray

Tetralogy of Fallot, RVH

20

Branching gram-positive rods with sulfur granules

Actinomyces israelii

21

Bronchogenic apical lung tumor on imaging

Pancoast tumor (can compress sympathetic ganglion and cause Horner syndrome)

22

“Brown” tumor of bone

Hyperparathyroidism or osteitis fibrosa cystica (deposited hemosiderin from hemorrhage gives brown color)

23

Cardiomegaly with apical atrophy

Chagas disease (Trypanosoma cruzi)

24

Cellular crescents in Bowman capsule

Rapidly progressive crescentic glomerulonephritis

25

“Chocolate cyst” of ovary

Endometriosis (frequently involves both ovaries)

26

Circular grouping of dark tumor cells surrounding pale neurofibrils

Homer-Wright rosettes (neuroblastoma, medulloblastoma, retinoblastoma)

27

Colonies of mucoid Pseudomonas in lungs

Cystic fibrosis (autosomal recessive mutation in CFTR gene -->Ž fat-soluble vitamin deficiency and mucous plugs)

28

Decreased AFP in amniotic fluid/maternal serum

Down syndrome or other chromosomal abnormality

29

Degeneration of dorsal column nerves

Tabes dorsalis (3° syphilis), subacute combined degeneration (dorsal columns and lateral corticospinal tracts affected)

30

Depigmentation of neurons in substantia nigra

Parkinson disease (basal ganglia disorder: rigidity, resting tremor, bradykinesia)

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