Rapid Review - Classic Presentations (1) Flashcards Preview

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Flashcards in Rapid Review - Classic Presentations (1) Deck (30):
1

Abdominal pain, ascites, hepatomegaly

Budd-Chiari syndrome (posthepatic venous thrombosis)

2

Achilles tendon xanthoma

Familial hypercholesterolemia (decreased LDL receptor signaling)

3

Adrenal hemorrhage, hypotension, DIC

Waterhouse-Friderichsen syndrome (meningococcemia)

4

Anterior “drawer sign” (+)

Anterior cruciate ligament injury

5

Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints

Marfan syndrome (fibrillin defect)

6

Athlete with polycythemia

2° to erythropoietin injection

7

Back pain, fever, night sweats, weight loss

Pott disease (vertebral TB)

8

Bilateral hilar adenopathy, uveitis

Sarcoidosis (noncaseating granulomas)

9

Blue sclera

Osteogenesis imperfecta (type I collagen defect)

10

Bluish line on gingiva

Burton line (lead poisoning)

11

Bone pain, bone enlargement, arthritis

Paget disease of bone (increased osteoblastic and osteoclastic activity)

12

Bounding pulses, diastolic heart murmur, head bobbing

Aortic regurgitation

13

“Butterfly” facial rash and Raynaud phenomenon in a young female

Systemic lupus erythematosus

14

Café-au-lait spots, Lisch nodules (iris hamartoma)

Neurofibromatosis type I (+ pheochromocytoma, optic gliomas)

15

Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities

McCune-Albright syndrome (mosaic G-protein signaling mutation)

16

Calf pseudohypertrophy

Muscular dystrophy (most commonly Duchenne): X-linked recessive deletion of dystrophin gene

17

“Cherry-red spots” on macula

Tay-Sachs (ganglioside accumulation) or Niemann-Pick (sphingomyelin accumulation), central retinal artery occlusion

18

Chest pain on exertion

Angina (stable: with moderate exertion; unstable: with minimal exertion)

19

Chest pain, pericardial effusion/friction rub, persistent fever following MI

Dressler syndrome (autoimmune-mediated post-MI fibrinous pericarditis, 1–12 weeks after acute episode)

20

Child uses arms to stand up from squat

Gowers sign (Duchenne muscular dystrophy)

21

Child with fever later develops red rash on face that spreads to body

“Slapped cheeks” (erythema infectiosum/fifth disease: parvovirus B19)

22

Chorea, dementia, caudate degeneration

Huntington disease (autosomal dominant CAG repeat expansion)

23

Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria

McArdle disease (muscle glycogen phosphorylase deficiency)

24

Cold intolerance

Hypothyroidism

25

Conjugate lateral gaze palsy, horizontal diplopia

Internuclear ophthalmoplegia (damage to MLF; bilateral [multiple sclerosis], unilateral [stroke])

26

Continuous “machine-like” heart murmur

PDA (close with indomethacin; open or maintain with misoprostol)

27

Cutaneous/dermal edema due to connective tissue deposition

Myxedema (caused by hypothyroidism, Graves disease [pretibial])

28

Dark purple skin/mouth nodules in a patient with AIDS

Kaposi sarcoma, associated with HHV-8

29

Deep, labored breathing/hyperventilation

Kussmaul respirations (diabetic ketoacidosis)

30

Dermatitis, dementia, diarrhea

Pellagra (niacin [vitamin B3] deficiency)

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