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Flashcards in Renal and Endocrine cases Deck (13):
1

What happens to ACTH produced by the pituitary in the presence of dexamethasone? What about an ectopic ACTH production?

Reduce if pituitary, no ACTH reduction if ectopic

2

What would happen to ACTH if the MC2R receptor did not function?

Higher, because there is no cort synthesis

3

What is the MOA of amenorrhea with cushings?

Cort inhibits CRH production in the hypotahlamus

4

What happens to insulin sensitivity in Cushing's?

Decreases due to chronic elevated BG levels

5

What is the effect of Cort on aldosterone?

Increases d/t enzyme saturation of 11beta-HSD2

6

How does Cushing's cause HTN?

Aldosterone synthesis

7

Why osteoporosis with Cushings?

Cort inhibits osteoblasts

8

What is the main control of prolactin?

Dopamine (inhibits it)

9

What are the two major chemicals that the prostate releases into the ejaculatory duct?

PSA
bicarb

10

What are the two major chemicals that the seminal vesicles release into the ejaculatory duct?

Fibrinogen and fructose

11

What does inhibin B repress in the male?

FSH

12

What is the other name for thyroxine-binding prealbumin?

Transthyretin

13

What is the other name for thyrotropin?

TSH