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Flashcards in Reproductive Physiology Deck (16)
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1

What is the normal range of menstrual cycle length?

21-35 days

2

How many days does menstruation usually last and how much blood is usually lost?

Average duration of menses 3-8 days
Normal estimated blood loss - approximately 30 ml

3

What day does ovulation usually occur in a 28 day cycle?

14

4

Describe what happens during follicular development?

Granulosa cells around egg enlarge
Release oestrogen
causes this uterine lining to thicken

5

What colour is the corpus luteum and why?

Luteum = latin for yellow
Due to cholesterol

6

When is the peak progesterone usually taken?

1 week after ovulation takes place

7

What attaches the ovary to the pelvic side wall?

IP ligament

8

Describe the release pattern of GnRH and its half life?

pulsatile manner
T1/2 = 2-4 mins

9

What enzyme is activated by FSH to promote the production of oestrogen?

Aromatase

10

What receptors does oestrogen act on?

- Induces FSH and LH receptors

11

What cells are acted on by LH?

Theca cells

12

Where is Activin found and what is its role?

Found in follicular fluid
Stimulates FSH induced oestrogen production

13

Where is inhibin found and what is its role?

- peptide in the follicular fluid
-ve feedback on FSH
- Locally enhances LH-induced androstenedione production

14

What cells are found in the seminiferous tubules of the testis?

Sertoli cells
Germ cells

15

What cells are found in the interstitium of the testes?

Leydig cells
Capillaries

16

Describe the process of fertilisation once the sperm meets the egg

- Chemotaxis
- Release of acrosomal enzymes
- Binding of sperm
- Passage through extracellular envelope
- Fusion of pronuclei