Respiratiry Disease In Occ Med Flashcards Preview

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Flashcards in Respiratiry Disease In Occ Med Deck (25):
0

Common causes of pneumoconiosis ?

Silicosis
Asbestosis
Coal workers' lung

1

Serpentine (curly fibers) vs Amphibole (needle-like), which is more carcinogenic?

Needle-like amphibole

2

Is cigarette smoke and asbestos synergistic for mesothelioma?

No

3

Does cig + asbestos increase the susceptibility for asbestosis?

Yes

4

Does Cig+ asbestos synergistic for bronchogenic cancer?

Yes

5

RR of lung cancer for
Non- somker+non-asbestos worker as 1, RR of lung cancer for asbestos worker is?

5.2

6

RR of lung cancer for
Non- somker+non-asbestos worker as 1, RR of lung cancer in smokers?

10.8

7

RR of lung cancer for
Non- somker+non-asbestos worker as 1, RR of lung cancer in smokers + asbestos workers?

53.2

8

X-Ray showing tiny round opacities primarily in the upper lung fields and hilar adenopathy, Eggshell calcification of hilar lymph nodes, is characteristic of what agent exposure?

Silicosis

(Eggshell calcification of hilar lymph nodes occurs in roughly 20% of cases)

9

Ferruginous bodies are associated with?

Asbestosis
But ferruginous bodies are not specific to the asbestos fiber and may result from a number of different types of foreign fibers.


10

Bagasse dust is associated with

Pulmonary fibrosis

11

Which herbicide can cause renal failure and rapid pulmonary fibrosis when ingested?

Paraquat

Often used to control marijuana growth

12

Cotton dust endotoxin

Or dust from other vegetable fibers such as flax, hemp, or sisal

Byssinosis ( Cotton worker's lung, Cotton bract disease, Mill fever, Brown lung)

Sx dyspnea and chest tightness

13

Ammonia, sulphur dioxide inhalation

Upper airway toxicity

14

Chlorine inhalation

Lower airway toxicity

15

Phosgene, nitrogen dioxide

Terminal airway

16

Irritant gases- water soluble

Primary upper-respiratory irritation
- Ammonia, chlorine, formaldehyde
- Sulfur dioxide

17

Irritant gases-water insoluble agent

Cause parenchymal lung damage, ARDS

Nitrogen oxide
Phosgene

18

Silo-filler's disease is caused by?

Nitrogen oxides

19

Mechanics that phosgene causes parenchymal lung damage?

Phosgene (COCl2) hydrolyzes in lung to HCl

20

Simple asphyxiants?

Reduce oxygen content.
Eg. CO2, methane, N2

21

Chemical asphyxiants ?

Interfere with cellular metabolism
Eg. CO, cyanide, H2S

22

Hypersensitivity pneumonitis (HP)

- A disease in which your lung become inflamed when you breathe in certain dusts to which you are allergic.
- The dust contains fungus spores from moldy hay or the dropping of birds.
- Most common type of HP is farmer's lung, from exposure to moldy hay, straw, and grain.

23

Chronic beryllium disease can be indistinguishable from ?

Sarcoidosis

- CXR similar: symmetric infiltrate, opacity es, interstitial scarring, and hilar node enlargement
- Distinguish the two rely on
- history of exposure and
- use of lymphocyte blast transformation test

24

Phosgene and oxides of nitrogen

- relatively lack of immediate signs
- frequently with delayed reaction
- pt exposed to significant concentration of these agent s should be observed for a minimum of 24 hours