Retroviruses (HIV, HTLV) PART 2 Flashcards Preview

Microbiology Block 1 > Retroviruses (HIV, HTLV) PART 2 > Flashcards

Flashcards in Retroviruses (HIV, HTLV) PART 2 Deck (19):
1

what is used to detect HIV?

ELISA

Complete Western Blot

p24 antigen ELISA

2

what technique can be used to detect viral nucleic acid?

PCR or RT-PCR

 

3

what can be used to detect the specific number of viral nucleic acid molecules?

qPCR

4

to screen for HIV you use what lab technique?

ELISA

5

to diagnose HIV what lab technique is used?

western blot

6

what lab technique is used to detect HIV virus in the blood?

RT-PCR

7

what lab technique is used to detect early marker of infection?

ELISA p24 antigen

8

what lab technique is used to detect the progression of HIV disease?

CD4 count

9

what are the HIV Nucleoside Reverse transcriptase inhibitors (NRTI)?

 

Zidivudine

 stavudine

 lamivudine

10

what are HIV protease inhibitor?

ritonavir

indinavir

nelfinavir

saquinavir

lopinavir

darunavir

11

Give examples of Highly Active Antiretroviral Therapy (HAART). (4)

 

Abacavir

zidovudine

lamivudine (Trizivir)

 

12

What recommended prophylactic regimens during HIV infection?

TMP-SMX (pneumocystis jirovecii)

Ganciclovir (CMV)

13

what kind of virus is HTLV?

human T lymphotropic virus is an oncogenic virus 

14

HTLV-1 is what kind of progressing oncovirus?

slow oncogenic virus

15

HTLV-1 will infect what cell? what will it cause them to do?

CD4 T cells

promotes their proliferation

16

What kind of cancer will HTLV-1 cause?

what is this cancer?

Adult T cell leukemia/lymphoma (ATLL)

this is a neoplasia of mature CD4 T cells

17

what are the signs of Adult T cell leukemia/lymphoma (ATLL) caused by HTLV-1?

bone lesions, 

lymphadenopathy, 

hypercalcemia, and 

skin rash

18

circulating malignant cells in Adult T cell leukemia/lymphoma (ATLL) caused by HTLV-1, will resemble?

flowers

A image thumb
19

if Adult T cell leukemia/lymphoma (ATLL) is diagnosed, what is the prognosis?

usually fatal within 1 year of diagnosis