+RNA enveloped (corona, Rubella, Toga, Flavi, Arboviruses)

Question 1

what is the second most common cause of the common cold?

Answer 1

corona viruses

Question 2

corona virus are responsible for these 2 disease?

Answer 2

1) SARS
2) MERS

Question 3

what is the clinical presentation of coronavirus?

Answer 3

upper respiratory tract infection

*no fever, cough, sore throat

Question 4

what cells does coronavirus infect primarily?

Answer 4

epithelial cells of the upper respiratory tract

Question 5

SARS is usually limited to a travel history of what?

Answer 5

toronto and far eash china

Question 6

what is the clinical presentation of SARS?

Answer 6

atypical pneumonia

fever

dyspnea and progressive hypoxia

diarrhea

Chest X ray shows patchy distribution of focal interstitial infiltrates

Question 7

what is another name for rubella?

Answer 7

3 day measles

Question 8

what is the biology of rubella?

Answer 8

envelped ss+RNA

Question 9

what cells will rubella infect?

Answer 9

respiratory cells

Question 10

what is the progression of infection?

Answer 10

1) it infects upper respiratory tract and spreads to lymph nodes
2) viremia and spread to whole body

Question 11

why does the rubella virus spread?

Answer 11

because of unvaccination

Question 13

what is the clinical presentation for rubella?

Answer 13

fever

coryza (runny nose)

conjunctiva (red eyes)

cough

erythematous maculo-papular rash

Question 14

when does the rubella rash disappear?

Answer 14

72 hours

Question 15

how does the erythematous maculo papular rash in rubella appear?

Answer 15

first on face and spreads to trunk

Question 16

how is rubella prevented?

Answer 16

through vaccine = MMR

Question 17

what causes this? what is this?

Answer 17

rubella, erythematous maculo papular rash

Question 18

what can be a complication that can happen with rubella?

Answer 18

congenita rubella syndrome

Question 19

what is congenital rubella syndrome?

Answer 19

rubella virus crosses placenta when “sero-negative”mother has primary infection.

Question 20

what determines the seriousness of congenital rubella syndrome?

Answer 20

the time period of infection

Question 21

what are some of the symptoms seen in congenital rubella syndrome?

Answer 21

thrombocytopenic purpura (blu-berry muffin baby)

microcephaly

mental retardation

cataracts

Question 22

what confirms a diagnosis of rubella?

Answer 22

presense of anti-rubella IgM or IgG

Question 23

what is the biology of Togavirus?

Answer 23

enveloped ss+RNA

Question 24

what are the 2 families of togavirus?

Answer 24

1) Arbovirus
2) Rubivirus

Question 25

how are togavirus transmitted?

Answer 25

mosquitoes

Question 26

what are the 3 viruses in togavirus?

Answer 26

1) EEE, WEE, VEE 2) Chikagunya 3) West Nile

Question 27

what symptom will EEE, WEE, VEE cause?

Answer 27

encephalitis

Question 28

what symptom will chikugunya cause?

Answer 28

joint pain and rash

Question 29

what symptom is seen in west nile virus?

Answer 29

encephalitis

Question 30

what mosquito causes EEE, WEE, VEE?

Answer 30

culex

Question 31

what mosquito causes chikugunya?

Answer 31

aedes

Question 32

what mosquito causes west nile?

Answer 32

culex

Question 33

what is the biology of flavivirus?

Answer 33

it is enveloped single stranded +RNA

Question 34

how is flavivirus transmitted?

Answer 34

mosquitoes (arthropod borne) and if transfusion of infected blood or transplantation

Question 35

what is the treatment for yellow fever?

Answer 35

vaccine

Question 36

when is arbovirus mostly affecting patients? (when are patients mostly going to be seen with this?)

Answer 36

summer

Question 37

what is the host for arbovirus? what is important about this?

Answer 37

humans, they are dead end host (once infect human it cannot further spread)

Question 38

what is the incubation period for EEE (eastern equine encephilitis), WEE (western equine encephilitis), VEE (venezuelan equine encephilitis)?

Answer 38

4-10 days

Question 39

what is the clinical presentation for EEE, WEE, VEE?

Answer 39

fever headache vomiting Tremors convulsions disorientation

Question 40

how is EEE, WEE, VEE different from herpes simplex virus?

Answer 40

there are no flu-like symptom preceding the symptoms

Question 41

how is the recovery for EEE, WEE, VEE?

Answer 41

complete when there is no central nervous system involvement.

Question 42

what is the clinical presentation for flavivirus?

Answer 42

tremor convulsions spastic paralysis

Question 43

what is the clinical presentation for dengue 1st time infection?

Answer 43

fever severe joint pain (1 week duration)

Question 44

what is the clinical presentatin for dengue haemorragic fever?

Answer 44

fever hemorrhagic manifestations thrombocytopenia leaky capillaries muscle and bone pain

Question 45

what is the clinical presentation for Dengue Haemorrhagic Shock Syndrome?

Answer 45

fever hemorrhagic manifestations thrombocytopenia leaky capillaries muscle and bone pain **shock**

Question 46

what is the clinical presentation of yellow fever?

Answer 46

Severe high fever, jaundice, GI bleeding (GI) “Black vomit”, shock failure of multiple organs.

Question 47

how is yellow fever prevented?

Answer 47

Attenuated Live-virus vaccine