-RNA enveloped (Hanta, Lassa, Rabies, Ebola) Flashcards Preview

Microbiology Block 1 > -RNA enveloped (Hanta, Lassa, Rabies, Ebola) > Flashcards

Flashcards in -RNA enveloped (Hanta, Lassa, Rabies, Ebola) Deck (30):
1

what virus are found in the bunya family?

La Cross

California encephalitis

Hanta virus

2

what viruses are found in the Arena virus family?

Lassa

LCMV

3

what viruses are found in the Rhabdo virus family?

rabies

4

what viruses are found in the filo family of viruses?

Ebola

5

what is the transmission of La Cross and California Encephalitis?

from squirrel to mosquito which will pass it to humans

6

what is the transmission of Hantavirus?

aerosolized mice urine

7

what is the transmission of Lassa virus?

through mice urine

8

what is the transmission of LCMV?

through mice urine

9

what is the transmission of rabies?

through saliva of mammals

10

what is the transmission of ebola?

humans and primates transmit it

among humans, infection occurs by body fluids

11

what is the clinical presentation of La Cross encephalitis?

fever, headache, vomiting, meningitis

12

what is the clinical presentation of california encephalitis virus?

fever, headache, vomiting, encephalitis

13

what is the clinical presentation of Hantavirus?

Hanta Pulmonary Syndrome:

  • flu-like symptoms
  • pulmonary edema
  • respiratory failure

Hemorrhagic Fever with renal syndrome (kidney necrosis, external bleeding)​

14

where is Lassa virus found?

West Africa

15

what is the clinical presentation for Lassa virus?

Lassa fever (high fever, bleeding gyms and blood vomiting, liver/spleen necrosis)

16

LCMV (lymphocytic choriomeningitis virus) will infect what mice?

house mice

17

what is the clinical presentation of LCMV?

fever, flu-like myalgia

18

what is the biology of the rabies virus?

eveloped BULLET SHAPED helical single stranded       -RNA

19

to what receptor will the VAP of rabies virus attach to?

nicotinic ACh receptor

20

What animal is most prone to infect with rabies?

raccoons and skunks

21

what happens with rabies once someone is infected?

virus can travel to CNS and to salivary glands

22

what is the clinical presentation of rabies during incubation?

flu-like symptoms

23

what is the clinical presentation of rabies after incubation?

neurological phase:

- itching at site of bite

- cerebral dysfunction 

- deliruim 

hydrophobia

24

what is the prognosis of rabies once clinical signs appear?

disease is fatal

25

what diagnosis tool can be used to confirm rabies?

what cytoplasmic inclusions can be found?

antibodies in the CSF

Negri bodies

26

what cytoplasmic inclusion is this?

Q image thumb

negri body

27

what cytoplasmic inclusion is this?

Q image thumb

negri bodies

28

what rabies vaccine is given before exposure to rabies virus?

killed vaccine 

29

what rabies vaccine is given after exposure to rabies virus?

what happens if you acquire the virus, when do you give the vaccine?

killed vaccine

human rabies immune globulin

when you acquire the virus, you must administer both vaccines before onset of symptoms

30

what is the clinical presentation of ebola?

extensive hemorrhage from GI and hypovolemic shock

and vomiting