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Flashcards in Rheum Deck (67)
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1

ankylosing spondylitis mainly affects

SI joints

2

ankylosing spondylitis more common in

males

3

ankylosing spondylitis associated with

IBD

4

bamboo spine on xray

ankylosing spondylitis

5

night pain and morning back stiffness relieved by exercise

ankylosing spondylitis

6

shiny or scaly skin over the interphalangeal joint

gottron's sign (dermatomyositis)

7

heliotrope rash, shiny/scaly extensor surfaces and interphalanges, difficulty getting dresses, voice change/difficulty swallowing

dermatomyositis

8

most common systemic vasculitis in children

HSP

9

palpable purpura, heme positive stool, colicky abdominal pain, hematuria

HSP

10

most common rheumatologic disease of childhood

JIA

11

JIA must present before what age

16 (at least 6 weeks in 1 joint)

12

morning stiffness with gradual loss of motion and rash

JIA

13

ANA in JIA

usually positive

14

JIA is more common in

girls

15

polyarthritis JIA

5 or more joints in the first 6 months, most females

16

oligoarthritis/pauciarthritis JIA

4 or fewer joints during the first 6 months, ANA positive, usually young females, associated with chronic uveitis, boys w/ HLA b27 have a better prognosis

17

systemic onset JIA

aka stills disease, affects males and females equally, extraarticular involvement is common

18

enthesitis related arthritis

SI joint pain, more common in boys, HLA-B27

19

first line JIA treatment

NSAID (indomethacin, ibuprofen, naproxen)

20

2nd line JIA treatment

steroids and immunosuppressants if NSAIDs don't work

21

MTX MOA

folate antagonist - side effects = GI distress and pulmonary toxicity

22

gold standard therapy for JIA

methotrexate

23

mucocutaneous lymph node syndrome aka

kawasaki's

24

Kawasaki is more common in

asian, males, around 2 years old, mostly winter and spring

25

Kawasaki's criteria

high fever for at least 5 days plus at least 4
- cervical LAD
- cracked lips
- non-exudative conjunctivitis
- polymorphous exanthem on trunk
- erythema/ desquamation of hands/feet

26

things common in Kawasaki that are not part of the criteria

sterile pyuria, migratory poly arthritis, gallbladder hydrops, thrombocytosis

27

thrombocytosis by what day with kawasaki

day 5

28

leukocytosis by what day with kawasaki

day 12

29

Kawasaki treatment

IVIG 2g/kg, initial high dose aspirin of 80mg/kg/day x24-48 hours then maintenance aspirin of 5 mg/kg/day x2 months

30

what vaccines can't be given after IVIG

varicella and MMR cannot be given for 11 months after IVIG