small test 3 Flashcards
two methods to examine the effect of analgesics on mice
- tail flick test
- hot plate test
what do you mimic if you give a pain causing substance IP
peritonitis
two groups of tranquilisers
- phenothiazine derivatives
- butyrophenones
three groups of sedatohypnotics
- alpha2 agonists
- benzodiazepines
- phenobarbital
why is ketamine an exception among anaesthetics
it has no muscle relaxation but has analgesia
neuroleptanalgesia, do you get unconsciousness
no, not good for surgery
whats ataranalgesia
BZD+ ket/ BZD +opioids, less sedation
aims of premedication
- sedation
- analgesia
- avoid pre/post narcotic excitation
premedication substances
- alpha2 agonists
- BZDs
- butorphanol, buprenorphine
- cont rate inf ketamine
definitions of epilepsy
- sudden
- transcient
- repetitive brain malfunction
treatment for status epilepticus
- diazepam
- phenobarbital
- levetiracetam
- propofol
- isoflurane
- ketamine
why is it a good idea to pair morphine with acapromazine
bc morphine induces high histamine release which can be counteracted by acepromazine
which species are more sensitive to alpha2 agonists
ruminants
what must we be aware of when using acepromazine
it can inhibit body temp regulation
why should azaperone only be administered IM
it is hypotensive
why shouldnt butyrophenones be used for transport to the slaughterhouse
they have a very long WP
phenothiazines sedation
++
phenothiazines analgesia
-, potentiate other analgesics
phenothiazines administration route
IV, IM, PO
phenothiazine derivatives indications
sedation, premedication, neuroleptanalgesia
phenothiazine derivatives side effects
inhibit vomiting, lowering blood pressure
phenothiazine derivatives contraindications
history of seizures,pseudopregnancy, dehydration
butyrophenones sedation
++
butyrophenones analgesia
slight
