systemic sclerosis Flashcards
(5 cards)
1
Q
features of limited cutaneous systemic sclerosis
A
raynauds
scleroderma affects face and distal limbs
anti-centromere antibodies
CREST: calcinosis, raynauds, oEsophafeal dysmobility, sclerodactylyl, telangiectasia
2
Q
features of diffuse cutaneous systemic sclerosis
A
scleroderma affects trunk and proximal limbs
anti-scl-70 antibodies
respiratory involvement- ILD, pulmonary arterial hypertension
renal disease and hypertension
3
Q
most common cause of death of diffuse cutaneous systemic sclerosis
A
respiratory involvement
4
Q
management of renal disease in diffuse systemic sclerosis
A
ACE inhibitor- captopril
5
Q
antibodies associated with systemic sclerosis
A
ANA positive- 90%
RF positive 30%
anti-scl-70- diffuse
anti-centromere- limited
