Transductance Flashcards

(58 cards)

1
Q

phototransduction

A

where engery in light waves (photons) stimulate photorecportor cells on the retina
this is whrer light energy is convted electorchemcia reposnse

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2
Q

what is at the base or rods and cones

A

synaptic ternaiom

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3
Q

do rods and cones contain a neucleous

A

yes

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4
Q

what makes up rodes and cones outer segmetn

A

sacks of discs / lamella which have photoreceptors called rhodopsin in rods

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5
Q

what is a a lameella made out of

A

a cell membarne

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6
Q

what makes up the cell membarne of a lamina in rods

A

visual pigment rhodospin =

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7
Q

what makes up the cel membare in cones

A

opsins s, m and l

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8
Q

what are opsin , s, ma and l responsible for

A

short - s
medium- m
l - large wavelenghts

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9
Q

wher eis opsin and retianl found in rhodosoin

A

intergal transmemare helical protin

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10
Q

where is vitamen a found in the eye

A

in the interagl transmemarb helical proin

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11
Q

what type of molcue is vitame a

A

isomere

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12
Q

what caue vitamen a to isomerise

A

light falling on it

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13
Q

what type of vitamen a cannot fit in t th eopsin

A

all trans retincal

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14
Q

what is the opsin

A

part of the interagl transmemabr helicap proin, the inner part, where retial is

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15
Q

what is the normal type of vitamen a in the eye

A

11 cis retinal (branched )

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16
Q

how does the viasl pigment result in phototransducation

A

phototransudion cascaste

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17
Q

what is the role of vit a in the visual pathway

A

visual regnariton

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18
Q

how is vitamen a mainly absobred

A

throug diet

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19
Q

what is the effect of vitamen a diffecty

A

will cause night blindnes, and damge to the normal epithlum

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20
Q

what is the cuase of vit a deficney

A

malnution
malabsip such as coeliac and spruce

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21
Q

signs of vit a dificeny

A

bitots sposts on conjuctivy
cornela ulcation

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22
Q

end stage vit a defecy

A

corneal melating
opopacification of the cornea

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23
Q

what type of cell conects rods to ganglion cell

A

bipolar nerve cell

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24
Q

what color cones are in tehe eye

A

red, green and blue

25
what is retinal
a vitamen a derivative
26
what is a rhodopsin made of
opsin and retinal
27
bleaching
when the retial changrs shape due to movement of light and no longer binds to opsin
28
what is the name of the catin chanesl in rods
cyclic nucleotide gated channels
29
what do the cyclic neuclotide grated channels do
allow na and ca to enerter k+ to leak out, cand voltage gated ca2+ channels
30
what happens to a rod when it is in darkness to cyclic gmp
cyclic gmp levls become high
31
what is the noramlm depolaris membaner potenal for rjhodopsin in darkness
-40 mv
32
how much neruo transmitter is realed at -40 in rhodpsin
there is alot of nurotaimsitor reese
33
how much nuortramiteor is readxed at -70mv
very little
34
what is the polarisioan of the cell in light
-70mv
35
what is retanl converion
where there are multiple rod cells conencted to one bipoalr cell
36
why is retanl conversion required
as it reduces the threashold for antion pototenal , in low light
37
low visual aquity
hard to see things in low light
38
type of pigment in cone cells
iodopsin - this is what gives it ability to sense colour
39
what type of light intentis cuase idropisn to be broken down
high light instnein
40
where are cones mainly found
in the forvea
41
are rods turned on or off with light
off
42
how many sub using tis rhoedopsin made up of
7
43
noraml retianl before it is changed
7 cis retainal (i.e. it is bent
44
what is the staright retial called
all trans retainal
45
what happens t teh rhodopin after the real hcnate shape
rhodopsin chanes shape
46
what does transducin do
when retianl chanes shape, it break away form rohdopin and joints to pde
47
wat does pde do
changes cyclic gmp to regualr gmp
48
what cause soidum change to open in rod cell
cyclic gmp, so more cyclic gmp mroe soidum enters cell
49
what happens when light hits on teh soudm chell
it decrease due to reduced cyclic gmp and the rods turn off
50
what are the 2 types of bioplar cells
light on and light off bipolar cells light on acitvated by decread decread glutamate dsecion, light on actaved by incerad gluatamt section
51
what is in an rod tip
lots of opttic discs
52
are there more rods or cones
rods - about 20 times more
53
where are rods mainly found
periphally of the eye ball
54
what vitimen is used to transform all trans retinal to 11cis retihnal
vitamen a
55
what is done with the bi products of 11cis regneraiton
becomes retinly esters used for retianl epithelum
56
name for all trans retinal
at rol
57
name for middle step between all trans retail and 11cis retinal
11 cis rol
58
name for 11cis retinal
11 cis ral