Trauma/ Miscell. and Neoplasia - Neuro Flashcards

(53 cards)

1
Q

trauma to CNS most concerning

A

contusion
injury to spinal cord bc of IVDD
equine wobbles

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2
Q

applied force and brain displacement are more severe than in a concussion

A

contusion

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3
Q

focal hemorrhage at the point of impact

A

coup

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4
Q

diffuse severe hemorrhage on the surface of the brain opposite to the point of impact

A

contrecoup

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5
Q

determines coup or contrecoup

A

amount of energy dissipated at the site of direct impact

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6
Q

impact from a small hard object

A

coup contusion

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7
Q

energy tends to dissipate at the impact site

A

coup contusion

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8
Q

impact from a larger object

A

contrecoup contusion

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9
Q

engery dissipated at the beginning or end of the head motion

A

contrecoup contusion

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10
Q

brain accelerates into the frontal and sphenoid plates

A

contrecoup lesion

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11
Q

thick zone of fibrous tissue surrounding the nucleus pulpsus

A

annulus fibrosus

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12
Q

central semi-solid mucoid connective tissue

A

nucleus pulposus

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13
Q

chondroid metaplasia & calcification of NP + tears/fissures in AF

A

IVVD Hansen Type 1

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14
Q

cause of Hansen Type 1 IVDD

A

mutation in FGF4

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15
Q

dehydration & collangenization of NP and degeneration of AF

A

IVDD Hansen Type 2

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16
Q

cause of IVDD Hansen Type 2

A

senility

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17
Q

lesions of Hansen Type 1 IVDD

A

acute rupture of AF
protrusion of NP into spinal canal
compression of the spinal cord, inflammation and nerve destruction

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18
Q

lesions of Hansen Type 2 IVDD

A

nuclear material escapes into the anuular area (bulging disk)

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19
Q

lesions of IVDD

A

hemorrhage
malacia
inflammation
embolism of disc material

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20
Q

embolism of disc material can cause what

A

fibrocartilaginous embolic myelopathy (FCEM)

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21
Q

compression on nervous tissue causing hypoxia-ischemia, necrosis and direct damage to compressed axons in horses

A

cervical vertebral malformation (CVM)
Wobbler syndrome

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22
Q

2 CVMs in horses

A

cervical static stenosis (CSS)
cervical vertebral instability (CVI)

23
Q

wobbler syndrome 8-18 months
C3 to C5
ventroflexion

A

cervical vertebral instability

24
Q

wobbler syndrome 1-4 years
C5-C7
static

A

cervical static stenosis

25
sequelae of Wobble syndrome
spinal cord compression myelomalacia ataxia
26
incidental finding in old dogs cerebral and spinal dura of elongated metaplastic plates of bone
ossifying pachymeningitis
27
lesions of ossifying pachymeningitis
ovoid thin whitish to mottled red
28
sequelae of ossifying pachmeningitis
pressure on spinal cord and nerve roots (Wallerian degeneration and necrosis) posterior paresis or paralysis
29
tail paralysis loss of sphincter tone -urinary bladder, rectum
neuritis of the cauda equina
30
lesions of neuritis of the cauda equina
serous neuritis of the cauda equina hyperemia hemorrhage fibrinous exudation
31
degeneration of the choroid plexus in old horses and not a true neoplasm
cholesteatosis
32
pathogenesis of cholesteatosis
post-inflammatory changes
33
lesions in lateral ventricles of cholesteatosis
cholesterol crystals cholesterol clefts fibrosis
34
most common primary neoplasm of the CNS in cats
meningiomas
35
most common neoplasm in cattle
nerve sheath cell tumors
36
most common neoplasm in dogs
gliomas
37
which breeds are more common to get gliomas
boxers boston terriers
38
CS of CNS Neoplasm
SOL = compression infiltration and tissue destruction hydrocephalus epilepsy behavioral changes
39
what are the primary neoplasms of the CNS
meningeal tumors glial tumors neuronal tumors embryonal tumors ependymoma
40
origin of menigeal tumors
arachnoid cells
41
growth by expansion compress but seldom invade well-demarcated, firm, encapsulated gray/white to red-brown
meningeal tumors
42
most common glial tumor
astrocytoma
43
site of astrocytoma
brain or spinal cord
44
variable appearance undetected well differentiated: poorly demarcated, firm, grey-white anaplastic: well-demarcated, soft & friable
astrocytoma
45
well-demarcated, gray to pink-red, soft/ gelatinous, cyst-like cellularly dense
oligodendroglioma
46
small cell malignant embryonal tumors neuronal/glial/ rarely mesenchymal
embryonal tumors
47
2 types of embryonal tumors
medulloblastoma neuroblastoma
48
unknown cell of origin arise from undifferentiated cells cerebellum cerebrum pons well-cricumscribed, soft, gray-pink
medulloblastoma
49
sequelae of medulloblastoma
hydrocephalus
50
origin ependymal cells large intracentricular masses well-demarcated, soft, gray-white, invasive, destruction gelatinous expansile mass
ependymoma
51
sequelae of ependymoma
cysts necrosis hemorrhage hydrocephalus
52
secondary metastatic neoplasms of the CNS
hemangiosarcoma mammary adenocarcinoma lymphosarcoma malignant melanoma squamous cell carcinoma
53