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Pathology II > Viral + Bacterial Inflammation - Neurology > Flashcards

Viral + Bacterial Inflammation - Neurology Flashcards

(60 cards)

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1
Q

inflammation of the meninges

A

meningitis

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2
Q

inflammation of the dura

A

pachymeningitis

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3
Q

inflammation of the pia-arachnoid

A

leptomeningitis

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4
Q

inflammation of the choroid

A

choroiditis

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5
Q

inflammation of the ependyma

A

ependymitis

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6
Q

most common route of infection of the CNS

A

hemtogenous

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7
Q

causes of infectious meningoencephalitis in cats

A

viral
fungal
rickettsial
protozoal

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8
Q

common non-infectious and immune-mediated inflammatory brain disorders

A

most common in dogs

lots of viruses

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9
Q

sequelae of inflammatory response

A

vascular response
perivascular cuffing
neuronal degeneratioin / death

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10
Q

type of exudates

A

suppurative
nonsuppurative
granulomatous
fibrionous

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11
Q

disease associated with suppurative exudate

A

bacterial infections
septic meningoencephalitis

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12
Q

consequences of abscess formation in the CNS

A

death
prolonged survival (one)
medullary abscesses (short course)

** space occupying lesions**

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13
Q

infections related to nonsuppurative exudates

A

viral infections
protozoa
parasites

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14
Q

responses to viral infection histologically

A

neuronal degeneration
perivascular cuffing by mononuclear cells
gliosis
** demyelination**

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15
Q

what viral disease is most commonly associated with demyelination

A

canine distemper
visna of sheep

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16
Q

what causes granulomatous exudates

A

fungi
higher bacteria

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17
Q

what virus is commonly associated with granulomatous exudates

A

FIP

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18
Q

which exudate is confined to the meninges and larger perivascular spaces

A

fibrinous exudare

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19
Q

what infection is often associated with fibrinous exudate

A

bacterial

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20
Q

purulent
bacterial in origin
diffuse

leptomeningitis, subarachnoid spaces, Virchow-Robin spaces and ventricles

A

meningitis

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21
Q

lesions of meningitis

A

purulent exudate
congestion / cloudy meninges
choroiditis + leptomeningitis
ventricular fluid (cloudy)

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22
Q

meningitis in calves, lambs, pigs, foals

A

E. coli

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23
Q

meningitis in cattle

A

H. somni

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24
Q

meningitis in various spp

A

Listeria moncytogenes

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25
single or multiple hemorrhagic foci in any part of the brain + heart and kidneys vasculitis thrombosis + septic infarction
thrombotic meningoencephalitis
25
meningitis and edema disease in pigs
C. perfringens type D
25
fever, depression, weakness, ataxia, blindness, polyarthritis H. somni
thrombotic meningoencephalitis
25
steps of TME
septicemia vasculitis neutrophils septic infarction (necrosis)
25
ascending infection of the trigeminal nerve encephalitis septicemia = hepatic necrosis +/- abortion
listeriosis
26
grayish foci of malacia in the medulla located in the brain stem (medulla oblongata and pons)
listeriosis
27
species listeriosis commonly is found in
sheep
28
C. perfringens type D in lambs
FSE
29
bilaterally symmetrical hemorrhage and softening of the basal ganglia lysis and liquefaction of white matter of frontal gyri
C. perfringens Type D
30
pathogenesis of C. perfringens Type D
epsilon toxin vascular injury edema hypoxia-ischemia necrosis
31
enterotoxemic colibacillosis in pigs
edema disease
32
progression of edema disease
toxin angiopathy vasculitis edema hypoxia-ischemia bilaterally symmertrical encephalomalacia (brainsteam)
33
CS of edema disease
incoordination hindlimb paralysis tremors convulsions
34
outcomes of intra-uterine infections
fetal death anomalies non-specific meningoencephalitis
35
outcomes of viral neonatal infectin
grey matter = lysis, necrosis, rapid death
36
outcomes of viral postnatal infection
white matter = chronic disease
37
depends on specific virus and cell surface receptors
localization of viral infections
38
histological changes due to viral infections
vascular reaction neuronal changes white matter meningitis inclusion bodies
39
histological viral vascular reactions
perivascular cuffing thrombosis large infiltrates non-specific
40
DDx of vascular reaction to inflammation
malacia immunological reactions
41
histological viral neuronal changes
non-specific neuronal degeneration
42
histological changes in viral white matter
2 degree involvment PVC, microgliosis demyelination (canine distemper)
43
histological changes of viral meningitis
focal or diffuse lymphocytic lymphoplasmacytic
44
viral inclusion bodies
intranuclear and / or intracytoplasmic specific for a disease
45
distemper inclusion body
intranuclear
46
rabies inclusion body
intracytoplasmic
47
most common inflammation of viral diseases
nonsuppurative inflammation
48
characteristics of viral disease inflammation
nonsuppurative inflammation neuronal degeneration perivascular cuffing gliosis ** not entirely specific**
49
rabies herpes arbovirus paramyxovirus
neurotropic viral infections
50
lesions of neurotropic viral infections
non-suppurative poliencephalitis poliomyelitis
51
CAE Maedi-Visna (lentivirus) EIA + FIP
viral granulomatous inflammation
52
lesions with viral granulomatous inflammation
macrophages with formation of granulomas
53
HC ICH EHV-1 MCF
viral vasculitis
54
lesions of viral vasculitis
damage to BV walls with hemorrhage and ischemic changes
55
distemper and old dog encephalitis FeLV FIV
viral leukoencephalitis
56
lesions of viral leukoencephalitis
destruction of white matter with virus-induced myelin degeneration

Pathology II (13 decks)

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