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Flashcards in usmle gold: misc Deck (64)
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1

Fastest growing tumor

Burkitt’s

2

PE’s are found in half of all

autopsies

3

Courvoisier’s Law:

tumors that obstruct the common bile duct cause enlarged gallbladders, but obstructing
gallstones do not (too much scarring), so if you can palpate the gallbladder you’e probably looking at cancer.

4

Only DNA virus to replicate in cytoplasm:

Pox

5

Only RNA virus to replicate in nucleus:

Influenza

6

Bacillus anthracis has the only

protein capsule

7

Bordetella pertussis (Whooping Cough) elicits

lymphocytosis rather than granulocytosis

8

Bronchioalveolar carcinomas grow without destroying

normal architecture of the lung

9

Cryptococcus neoformans often lacks a

capsule and, when stained with GMS, looks just like Pneumycistis
carinii, except that Cryptococcus lacks the prominent nucleoli.

10

Weil Felix reaction:

(+)R. rickettssi & (+)Proteus vulgaris & P. mirabilis

11

Treponema pallidum (Syphilis) tests:

1)VDRL 2)FTA-Abs: most widely used 3)TPI (immobilization test – most
expensive but the Gold Standard)

12

IL 1

Monocytes, macrophages
Stimulates T cell proliferation & IL2 produciton

13

IL 2

Macrophages, T & NK cells Stim prolif of B, T & NK cell

14

IL 3

T cells
GF of tissue mast cells & hematopoietic stem cells

15

IL 4

T cells
↑ growth of B & T cells/ ↑ HLA II Ags

16

IL 5

T cells
Maturation of B ! plasma cell

17

IL 6

T cells, monocytes
Maturation of B & T cell/ (-) fibroblasts

18

IFN α

B cells, macrophages
Antiviral activity

19

IFN β

Fibroblasts
Antiviral activity

20

IFN gamma

T & NK cells
Antiviral activity, (+) macrophages, ↑ HLA II Ags

21

TNF α

Macrophages, T & NK cells
T cell prolif, IL 2 prod, cytotoxicity

22

TNF β

T cells
T cell prolif, IL 2 prod, cytotoxicity

23

VHL

3p
Von Hippel Lindau, Renal Cell CA

24

APC

5p
Familial adenomatous polyposis, Colon CA

25

WT-1

11p
Wilm’s tumor

26

Rb

13q
Retinoblastoma, Osteosarcoma

27

BRCA-2

13q
Breast CA

28

p53

17p
Most human Cas

29

NF-1

17q
Neurofibromatosis type 1

30

BRCA-1

17q
Breast CA, Ovarian CA