usmle gold: misc Flashcards

(64 cards)

1
Q

Fastest growing tumor

A

Burkitt’s

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2
Q

PE’s are found in half of all

A

autopsies

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3
Q

Courvoisier’s Law:

A

tumors that obstruct the common bile duct cause enlarged gallbladders, but obstructing
gallstones do not (too much scarring), so if you can palpate the gallbladder you’e probably looking at cancer.

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4
Q

Only DNA virus to replicate in cytoplasm:

A

Pox

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5
Q

Only RNA virus to replicate in nucleus:

A

Influenza

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6
Q

Bacillus anthracis has the only

A

protein capsule

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7
Q

Bordetella pertussis (Whooping Cough) elicits

A

lymphocytosis rather than granulocytosis

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8
Q

Bronchioalveolar carcinomas grow without destroying

A

normal architecture of the lung

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9
Q

Cryptococcus neoformans often lacks a

A

capsule and, when stained with GMS, looks just like Pneumycistis
carinii, except that Cryptococcus lacks the prominent nucleoli.

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10
Q

Weil Felix reaction:

A

(+)R. rickettssi & (+)Proteus vulgaris & P. mirabilis

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11
Q

Treponema pallidum (Syphilis) tests:

A

1)VDRL 2)FTA-Abs: most widely used 3)TPI (immobilization test – most
expensive but the Gold Standard)

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12
Q

IL 1

A

Monocytes, macrophages

Stimulates T cell proliferation & IL2 produciton

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13
Q

IL 2

A

Macrophages, T & NK cells Stim prolif of B, T & NK cell

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14
Q

IL 3

A

T cells

GF of tissue mast cells & hematopoietic stem cells

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15
Q

IL 4

A

T cells

↑ growth of B & T cells/ ↑ HLA II Ags

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16
Q

IL 5

A

T cells

Maturation of B ! plasma cell

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17
Q

IL 6

A

T cells, monocytes

Maturation of B & T cell/ (-) fibroblasts

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18
Q

IFN α

A

B cells, macrophages

Antiviral activity

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19
Q

IFN β

A

Fibroblasts

Antiviral activity

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20
Q

IFN gamma

A

T & NK cells

Antiviral activity, (+) macrophages, ↑ HLA II Ags

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21
Q

TNF α

A

Macrophages, T & NK cells

T cell prolif, IL 2 prod, cytotoxicity

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22
Q

TNF β

A

T cells

T cell prolif, IL 2 prod, cytotoxicity

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23
Q

VHL

A

3p

Von Hippel Lindau, Renal Cell CA

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24
Q

APC

A

5p

Familial adenomatous polyposis, Colon CA

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25
WT-1
11p | Wilm’s tumor
26
Rb
13q | Retinoblastoma, Osteosarcoma
27
BRCA-2
13q | Breast CA
28
p53
17p | Most human Cas
29
NF-1
17q | Neurofibromatosis type 1
30
BRCA-1
17q | Breast CA, Ovarian CA
31
DCC
18q | Colon & Stomach CA
32
DPC
18q Pancreatic CA
33
NF-2
22q Neurofibromatosis type 2 = bilateral acoustic neuroma
34
Resistance in Series:
Add all
35
Resistance in Parallel:
Invert the answer
36
Filtration Fraction =
GFR/RPF
37
GFR:
Glomerular Filtration Rate
38
RPF:
Renal Plasma Flow
39
Filtered Load =
GFR x [Conc]
40
Excretion Rate =
[Urine] x VelUrine
41
Clearance =
[Urine] x Vel(Urine) / [plasma] or Excretion / [Plasma]
42
Clearance of PAH =
[ERPF]
43
ERPF:
Eff renal plasma flow
44
Renal Blood Flow =
ERPF / 1 - Hct
45
Free Water Clearance =
VelUrine - Urine(osm) x Vel(urine) / P(osm)
46
CO =
HR x SV
47
CO =
O2(consumed) / PulmonaryA VO difference
48
Pulse Pressure =
Systolic – Diastolic
49
MAP =
Diastolic + 1/3 Pulse Pressure
50
CO =
MAP / TPR
51
MAP =
TPR x CO
52
F =
P1− P2 / R
53
PAO2 =
(760 – 47) FO2 - (PACO2 / R) ``` FO2 = [O2] PACO2 = Alv. Press. Of CO2 R = Resp. Exchange Ratio CO2 produced / O2 consumed ≅ .8 or 1 ```
54
Flow =
O2 consumed / AtoVO difference
55
Velgas Diffusion =
(Area / thickness) x Gas Diffusion Constant x Difference of Partial Pressure
56
VentTot =
VentTidal x #of Respirations
57
VentAlv =
(VentTidal – VentDead) x # of Respirations
58
Compliance =
Vol / Press
59
P =
Tension / Radius
60
1.0 =
Va/Q
61
Diffusing Capacity =
COuptake / PACO2
62
Resp Doubles:
150mmHg & 40mmHg
63
New PCO2 =
20
64
New PO2 =
170