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Flashcards in gold usmle: Pathology Deck (234)
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1

Mobitz I

Usually due to inferior MI. Rarely goes into 3rd degree block.
118. Txt w/ Atropine or Isoproterenol.

2

Mobitz II

BBB association. Often goes to 3rd degree AV block. Usually due to anterior MI.

3

P wave

Atrial depol.

4

a wave

LA contraction

5

T wave

Vetricular repol.

6

Wavy fibers

Eosinophilic bands of necrotic myocytes. Early sign of MI.

7

Janeway’s lesions

Acute bacterial endocarditis.
125. Nontender, erythematous lesions of palms & soles.

8

Osler’s nodes

Subacute bacterial endocarditis.
127. Tender lesions of fingers & toes.

9

Thiamine defcy

Wet Beri Beri heart. Dilated (congested) cardiomyopathy due to chronic alcohol consumption
129. Dyr Beri Beri = peripheral neuropathy
130. Wernicke-Korsakoff = ataxia; confusion; confabulation; memory loss

10

Fibrinous Pericarditis

Associated w/ MI: Dressler’s

11

Serous Pericarditis

Associated w/ nonbacterial; viral (Coxsackie) infection; immunologic reaction.

12

Friction Rub

Pericarditis association

13

Hemorrhagic Pericarditis

Associated w/ TB or neoplasm

14

Restrictive Cardiomyopathy

Aka infiltrative cardiomyopathy that stiffens the heart
136. Due to amyloidosis in the elderly
137. Due to , also see schaumann & asteroid bodies in young (

15

PML’s infectious agent

JC Virus (Papovavirus = dsDNA, naked icosahedral capsid)

16

Edema

↑Pc (more seeps out)
140. ↓πc (less reabsorbed)
141. ↑ permeability
142. Block lymphatic drainage

17

Adult Polycystic Kidney
Disease

Commonly see liver cysts & Berry aneurysms along w/ kidney cysts. Hematuria & HTN also present.
144. 3 cysts in ea. Kidney w/ + family history confirms diagnosis

18

Malignant HTN & Kidneys

Petehial hemorrhages are seen on kidney surfaces = Flea-Bitten surface = young black men

19

Nephritic signs

Hematuria; RBC casts; HTN

20

Nephrotic signs

Proteinuria; Hypoalbuminemia; Edema

21

Podocyte Effacement seen
w/

Minimal Change (Lipoid nephrosis) disease

22

ASO seen in

Acute post-streptococcal GN (due to βHGASrtep)
150. Anti streptolysin O

23

Crescentic GN

Rapidly progressive GN – nephritic syndrome
152. Associated w/ multi system disease or post-strep/post infectious glomerular nephritis

24

Hereditary Nephritis

Alport’s syndrome. X linked
154. Renal disease w/ deafness & ocualr abnormalities

25

Membranoproliferative GN

Can be secondary to complement deficiency; chronic infections; CLL
156. See tram tracking

26

TypeI Membrano
Proliferative GN deposits

C3 & IgG deposits

27

TypeII Membrano
Proliferative GN deposits

Only C3 deposits
159. Aka Dense deposit disease

28

Focal segmental
glomerulosclerosis deposits

IgM & C3 deposits

29

Cold agglutinins

Seen in atypical pneumonia
Mycoplasma pneumoniae
162. It is IgM Ab with specificity for I Ag on adult RBCs

30

Scrofula

TB in the lymph nodes