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Y2 Dermatology > Viral Infections > Flashcards

Flashcards in Viral Infections Deck (36)
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1

Cause of slapped cheek syndrome

Parvovirus B-19

2

Treatment of ophthalmic zoster

acyclovir - drops or tablets - may prefer tablets as less epithelial toxic

3

Complications of Parvovirus B-19

spontaneous abortion, aplastic crisis, chronic anaemia

4

What predicts the severity of chicken pox

extremes of age and depressed cell mediated immunity

5

Causes of erythema multiform

HSV, drug eruptions, mycoplasma pneumonia bacteria

6

Virus causing chicken pox and shingles

varicella zoster

7

What medications should be avoided in chicken pox?

ibuprofen (necrotising fasciitis/secondary skin infection), aspirin (reye's syndrome - leads to liver and brain swelling)

8

Presentation of chicken pox

generalised rash and fever, itch

9

What is eczema herpeticum?

the spread of herpes simplex virus to an area of eczema

10

Patients at risk of aplastic crisis

thalassaemia, sickle cell, hereditary spherocytosis

11

Sign of ophthalmic zoster

Hutchison's sign - acute red eye + spots on the nose

12

Cause of molluscum contagiosum

pox virus

13

Presentation of Parvovirus B-19 in children

slapped cheek rash which may also occur on limbs

14

pain lasting longer than 4 weeks after shingles is called...?

post-herpetic neuralgia

15

How may the chicken pox vaccine help with shingles?

reduces the amount of shingles and associated post-herpetic neuralgia in >70s, routinely given

16

Most common groups to have shingles

elderly and immunocompromised

17

Presentation of erythema multiform

target lesions with erythema

18

complication of shingles...

ophthalmic zonster

19

where does a recurrent herpes simplex virus usually appear?

around the vermillion border of the mouth

20

Presentation of Parvovirus B-19 in adults

Polyarthritis of the small joints - may occur without the rash

21

how does shingles present?

tingling/pain --> erythema --> vesicles in a dermatomal distribution

22

How does acyclovir work to treat varicella zoster and herpes simplex viruses?

it is a guanosine analogue which is incorporated into the DNA and thus inhibits replication. It does not eradicate latent virus

23

Presentation of molluscum contagiousum

small pink papules with a depressed central punctum

24

What does the herpes simplex virus cause?

primary gingivostomatitis - ulceration in and around the mouth

25

Which type of herpes simplex virus does this describe: main cause of oral lesions, 50% of genital warts, encephalitis?

Herpes simplex type 1

26

How is molluscum contagiosum treated?

it is self-limiting but may take months

27

Where does the varicella zoster virus establish latency?

the sensory nerve roots

28

What type of vaccination is the chicken pox vaccine?

Live attenuated - not routinely given in UK

29

complications of chicken pox (4)

secondary bacterial infection, pneumonitis, scarring, encephalitis

30

What sort of pain is produced by shingles?

neuralgia