Eczema and Dermatitis Flashcards Preview

Y2 Dermatology > Eczema and Dermatitis > Flashcards

Flashcards in Eczema and Dermatitis Deck (37)
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1

Investigation for allergic contact dermatitis?

patch testing

2

Distribution of atopic eczema in older children and adults

flexural surfaces

3

What is this condition?

Contact allergic dermatitis

4

Common infections associated with eczema? (2)

staph. aureus; herpes simplex virus

5

Difference between contact allergic and irritant dermatitis

Irritant does not require prior exposure and may occur due to milder irritants

6

T cells affected in eczema

Th2

7

Clues that allergic contact dermatitis may be workplace associated?

clears up on holiday

8

More extreme treatment of eczema

phototherapy, immunosuppressants and biologic agents

9

Appearance of eczema herpeticum

monomorphic punched out lesions

10

Condition where eczema and herpes simplex virus are combined

eczema herpeticum

11

Pathogenic mechanism behind allergic contact dermatitis

langherhans cells process and present the antigen at the regional lymph nodes and activate naive CD4 T cells. This results in the production of effector and memory T cells which produce a response to future exposures within 48-96 hours.

12

Atopic eczema is associated with what other diseases? (3)

asthma, allergic rhinitis, food allergy

13

Example of emollients

Diprobase, Dermol, Epaderm, E45

14

Appearance of skin in a person with eczema

dry, erythematous, scaling, lichenification, excoriations

15

Allergic contact dermatitis requires...?

prior exposure

16

Diagnostic criteria for eczema is itching plus 3 or more of...?

visible flexural rash (children/adults), history of a flexural rash, PMH or close family history of atopy, generally dry skin, onset before age 2

17

Papule

raised area <0.5cm

18

What is this condition called?

Atopic eczema 

19

Treatment of allergic contact dermatitis?

avoidance; topical steroids where more severe; topical calcineurin inhibitors and emollients to moisturise

20

Common condition associated with allergic contact dermatitis?

atopic eczema

21

Localisation of a rash associated with allergic contact dermatitis?

tends to be localised to areas of exposure

22

Common workforces to be affected by allergic contact dermatitis?

hairdresses; beauticians; manual and farm labourers, health care professionals, cleaners, food industry workers

23

Discoid eczema in brief

eczema in unusual but well defined disc shape

24

Treatment for eczema herpeticum

IV antivirals i.e. aciclovir

25

Protein highly affected in eczema

Filaggrin

26

Common presentation of allergic contact dermatitis

pruritis, erythema, vesicles/bullae (rare but may also have: urticaria, pustules, lichenoid lesions and ulceration)

27

Cytokines affected by eczema

IL - 4, 5, 13

28

Spongiosis

oedema between the keratinocytes

29

Appearance of eczema with staph. aureus

golden crusting around infected area

30

Distribution of atopic eczema in young babies and infants

cheeks, scalp, extensor surfaces, neck