week 10 pharm Flashcards
between captopril and candesartan, which drugs lowers GFR
only captopril
how does captopril help with CKD
it lowers BP to prevent further damage to small blood vessels of the kidney
what drug class is candesartan
angio receptor blocker (ARB)
whats the main difference between captopril and Candesartan
candesartan does exactly what captopril does, but it blocks angio 2 instead of ACE so it doesn’t cause a cough
captopril is also better researched
how does atorvastatin help with CKD
because CKD can cause dyslipidemia (difficulty synthesising lipids) this drug helps get rid of it so there isn’t excess in the body
what are 2 lab values you should monitor for a patient on atorvastatin
LFTs because it can cause hepatotoxicity
Creatinine Kinase because it can cause rhabdomylysis
when would you see atorvastatin start working
within 2 weeks of starting the drug
can you use furosemide if GFR is low
yes
what is the lasix challenge
if all else fails, we use lasix to kick kidneys into action
what urine output constitutes anuria
less than 40cc/hr
what is ototoxicity and which drug causes it
ringing in the ears caused by furosemide
why is hydrochlorothiazide weaker than furosemide
because its farther from the glomerulus
which GFR contraindicates hydrochlorothiazide
less than 15-20
which GFR contraindicates spironolactone
less than 30
how does erythropoetin help with CKD
CKD can cause anemia, so this drug stimulates RBCs in the bone marrow
