Flashcards in Week 6 part 1 Deck (93)
Characterised by a complex papillary and/or glandular archietecture with diffuse, marked nuclear pleomorphism
Serous carcinoma of endometrium
Treatment of endometrial carcinoma?
Endometrioid carcinoma are primarily graded by architecture - what are the three grades?
1. 5% or less solid growth
2. 6-50% solid growth
4. >50% solid growth
What is description of stage I endometrial cancer?
COnfiend to uterus
What stage of endometrial cancer does it involve vaginal or parametrial involvement?
IIIB, IIIC is metastases to pelvic and/or paraaortic lymph nodes
What endometrial cancaer? Heterologous elements commonly seen in about 50% cases (rhabdomyosarcoma, chrondrosarcoma, osteosarcoma)
The presence of a rhabdomyosarcomatous component has the worst prognosis
A malignant smooth muscle tumour commonly displaying a spindle cell morphology
Leiomyosarcoma - the most common uterine sarcoma
What type of ovarian cysts are polycyctic ovaries?
Endometriosis on ovary
Peritoneal spots or nodules
What are epithelial ovarian tumours catogorised as?
Benign, borderline or malignant
What epithelial ovarian tumour class is this: no cytological abnormalities, proliferative activity absent, no stromal invasion?
What epithelial ovarian tumour class is this: cytological abnomralities, proliferative, no stromal invation
What epithelial ovarian tumour class is this: stromal invasion?
What are the two types of serous carcinoma of ovary?
What grade of serous carcinoma of ovary involves serous tubal intraepithelial carcinoma?
What are endometrioid and clear cell carcinoma of ovary strongly associated iwth?
Endometriosis of ovary
What is the diagnosis of endometrioiud and clear cell ovarian carcinoma often made on?
An ovarian tumour of transitional type epithelium, usually benign
Give two types of germ cell ovarian tumours?
Dermoid cyst - mature, benign, cystic
What are 95% of ovarian germ cell tumours?
Dermoid cysts - cystic, containing sebum and hair
most common malignant primitive germ cell tumour
1-2% of all malignant ovarian tumours
Almost exclusively children and young women, average age 22
A type of ovarian sex cord/stromal tumour which is benign, may produce oestrogen causing uterine bleeding?
What ovarian sex cord/stromal tumours are rare and may produce androgens?
Sertoli-Leydig cell tumours
What must be considered in all cases of ovarian tumours if they are bilateral and small?
Metastatic tumours - stomach, colon, breast, pancreas
In FIGO staging of ovarian cancer - what is IA
tumour confined to one ovary
In FIGO staging of ovarian cancer - what is IB
tumour confined to both ovaries
In FIGO staging of ovarian cancer - what is IC
Cancer involving ovarian surface/rupture/siurgical split/tumour in washings
In FIGO staging of ovarian cancer - what is 2A
extension or implants on uterus/fallopian tube