Flashcards in Week 6 part 1 Deck (93)
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61
Characterised by a complex papillary and/or glandular archietecture with diffuse, marked nuclear pleomorphism
Serous carcinoma of endometrium
62
Treatment of endometrial carcinoma?
Hysterectomy: chemo/radiotherapy
63
Endometrioid carcinoma are primarily graded by architecture - what are the three grades?
1. 5% or less solid growth
2. 6-50% solid growth
4. >50% solid growth
64
What is description of stage I endometrial cancer?
COnfiend to uterus
65
What stage of endometrial cancer does it involve vaginal or parametrial involvement?
IIIB, IIIC is metastases to pelvic and/or paraaortic lymph nodes
66
What endometrial cancaer? Heterologous elements commonly seen in about 50% cases (rhabdomyosarcoma, chrondrosarcoma, osteosarcoma)
The presence of a rhabdomyosarcomatous component has the worst prognosis
Carcinosarcoma
67
A malignant smooth muscle tumour commonly displaying a spindle cell morphology
Leiomyosarcoma - the most common uterine sarcoma
68
What type of ovarian cysts are polycyctic ovaries?
Follicular
69
Chocolate cyst?
Endometriosis on ovary
70
Peritoneal spots or nodules
Fibrous adhesions
Chocolate cysts
Ovarian endometriosis
71
What are epithelial ovarian tumours catogorised as?
Benign, borderline or malignant
72
What epithelial ovarian tumour class is this: no cytological abnormalities, proliferative activity absent, no stromal invasion?
Benign
73
What epithelial ovarian tumour class is this: cytological abnomralities, proliferative, no stromal invation
Borderline
74
What epithelial ovarian tumour class is this: stromal invasion?
Malignant
75
What are the two types of serous carcinoma of ovary?
High grade
Low grade
76
What grade of serous carcinoma of ovary involves serous tubal intraepithelial carcinoma?
hIGH grade
77
What are endometrioid and clear cell carcinoma of ovary strongly associated iwth?
Endometriosis of ovary
Lynch syndrome
78
What is the diagnosis of endometrioiud and clear cell ovarian carcinoma often made on?
Ascitic fluid
79
An ovarian tumour of transitional type epithelium, usually benign
Brenner tumour
80
Give two types of germ cell ovarian tumours?
Dermoid cyst - mature, benign, cystic
Teratoma
81
What are 95% of ovarian germ cell tumours?
Dermoid cysts - cystic, containing sebum and hair
82
most common malignant primitive germ cell tumour
1-2% of all malignant ovarian tumours
Almost exclusively children and young women, average age 22
Dysgerminoma
83
A type of ovarian sex cord/stromal tumour which is benign, may produce oestrogen causing uterine bleeding?
Fibroma/thecoma
84
What ovarian sex cord/stromal tumours are rare and may produce androgens?
Sertoli-Leydig cell tumours
85
What must be considered in all cases of ovarian tumours if they are bilateral and small?
Metastatic tumours - stomach, colon, breast, pancreas
86
In FIGO staging of ovarian cancer - what is IA
tumour confined to one ovary
87
In FIGO staging of ovarian cancer - what is IB
tumour confined to both ovaries
88
In FIGO staging of ovarian cancer - what is IC
Cancer involving ovarian surface/rupture/siurgical split/tumour in washings
89
In FIGO staging of ovarian cancer - what is 2A
extension or implants on uterus/fallopian tube
90
