Wk1 Parathyroid Path Flashcards Preview

Endo/Repro > Wk1 Parathyroid Path > Flashcards

Flashcards in Wk1 Parathyroid Path Deck (16):
1

upper pair of glands originates where?

4th pharyngeal pouch

2

lower pair of glands originates where?

3rd pharyngeal pouch

3

little dark cells that secrete PTH

chief cells

4

big pink cells that don't do shit

oxyphils

5

Bottom line with PTH:

raises serum Ca++

6

What controls PTH release:

free Ca++

7

Most common cause of SYMPTOMATIC hypercalcemia:

malignancy

8

most common cause of Asymptomatic hypercalcemia:

hyperparathyroidism

9

Three causes of primary hyperparathyroidism:

1. parathyroid adenoma

2. hyperplasia

3. carcinoma

10

Sx of hyperparathyroidism:

Stones

Bones -- pain, browm tumors (blood)

Groan -- GI probs

Moan -- mental changes

11

lab findings in primary hyperparathyroidism:

high PTH

high Ca++

low phosphate

12

Commonest cause of primary hyperthyroidism:

adenoma

13

two gene defects possible in adenoma

PRAD 1 -- overexpression

MEN 1 -- loss or mutation

14

Definition and causes of secondary hyperparathyroidism:

**chronic hypocalcemia

-renal failure

- diet low in Ca

- vit D defeciency

15

tap facial nerve --> spasm

Chvostek sign

hypoparathyroidism -- low Ca

16

carpel spasm with BP cuff

Trouseau sign

hypoparathyroidism -- low Ca