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Donald Gygi
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Decks in this class (30)
Lymph Drainage
Cervical lymph node cluster drains,
Hilar lymph node cluster drains,
Mediastinal lymph node cluster dr...
14
cards
Autoantibodies
Myasthenia gravis is associated w...,
Goodpasture syndrome is associate...,
Antiphospholipid syndrome is asso...
26
cards
Spleen
Secondary immune organ located in...,
Secondary immune organ located an...,
Secondary immune organ protected ...
14
cards
Thymus
Location of thymus,
Function of thymus,
Thymus is derived from
9
cards
Innate vs Adaptive Immunity
Components of innate immunity,
Duration of innate immunity resis...,
Innate immunity response to patho...
13
cards
Major Histocompatibility Complex I and II
Features of major histocompatibil...,
Mhc loci,
Mhc i binds to
15
cards
HLA subtypes associated with diseases
Hla associated with hemochromatosis,
Hla associated with addison disease,
Hla associated with myesthenia gr...
17
cards
Natural Killer cells
Lymphocyte member of innate immunity,
Target of nk cells,
Mechanism nk cells induce apoptosis
6
cards
Major function of B and T cells
Type of b cell immunity,
Purpose of somatic hypermutation,
Differentiated b cell
15
cards
Differentiation of T cells
Area of t cell positive selection,
Area of t cell negative selection,
T cells expressing tcrs capable o...
12
cards
Helper T cells, Cytotoxic T cells, Regulatory T cells
Differentiated helper t cell,
Cytokine that causes t cell to ch...,
Cytokine that causes t cell to ch...
22
cards
T and B cell activation
Apc cell types,
Steps for apc to present antigen ...,
Activation of cd4 t cell
6
cards
Antibody structure and function
Section of antibody that contains...,
Section of antibody that consists...,
Section of antibody that determin...
14
cards
Immunoglobulin Isotypes
Main antibody in secondary delaye...,
Most abundant immunoglobulin in s...,
Which immunoglobulin provides inf...
25
cards
Antigen type and memory
Vaccines that are weakly immunoge...,
Antigens containing a protein com...,
Strong immunogenic antigens
4
cards
Acute-phase reactants
Cytokine that induces acute phase...,
Factors produced by liver in both...,
Opsonin that fixes complement and...
10
cards
Complement and Complement Disorders
Function of mac,
Classic pathway,
Alternative pathway
20
cards
Important Cytokines
Cytokine that causes fever and st...,
Major chemotactic factor for neut...,
Induces differentiation of t cell...
20
cards
Respiratory burst (oxidative burst)
Enzyme that converts o2 superoxid...,
Enzyme that converts h2o2 to hclo...,
Enzyme that reduces gssg to gsh
11
cards
Interferon alpha and beta
Glycoproteins that are part of th...,
Site of interferon synthesis,
Mechanism of interferons
3
cards
Cell surface proteins, effects of bacterial toxins, antigenic variation
Which cells express mhc i,
Cell surface protein located on t...,
Cell surface protein located on t...
31
cards
Passive vs Active immunity, Vaccination
Immunity that involves receiving ...,
Immunity that involves exposure t...,
Onset of passive immunity
28
cards
Hypersensitivity types
Mast cells and basophils releasin...,
Type i hypersensitivity reaction ...,
Reaction of type i hypersensitivi...
38
cards
Blood transfusion reactions
Patient presents with urticaria p...,
Patient presents with fever heada...,
Febrile nonhemolytic transfusion ...
9
cards
Immunodeficiencies
Disorder with recurrent bacterial...,
Findings include absent b cells i...,
Caused by a defect in btk tyrosin...
84
cards
Infections in immunodeficiency
T cells deficiencies predispose t...,
B cells deficiencies predisposes ...,
Encapsulated organism cause infec...
13
cards
Grafts and Transplant rejection
Autograft donor,
Syngeneic draft donor,
Allograft donor
30
cards
Immunosuppressants
Immunosuppressants that block t c...,
Calcinuerin inhibitor that bind f...,
Calcinuerin inhibitor that binds ...
51
cards
Recombinant cytokines and clinical uses
Erythropoietan recombinant cytoki...,
Il2 recombinant cytokine used in ...,
G csf recombinant cytokine used i...
10
cards
Therapeutic antibodies
Alemtuzumab target,
Alemtuzumab clincal uses,
Bevacizumab target
35
cards
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step 1 immunology-first aid 2017
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