Major function of B and T cells

Question 1

Type of B-cell immunity

Answer 1

Humoral immunity

Question 2

Purpose of somatic hypermutation

Answer 2

Optimize antigen specificity to recognize antigen

Question 3

Differentiated B-cell

Answer 3

Plasma cell

Question 4

Function of Plasma cell

Answer 4

Secrete specific immunoglobulins (antibodies): IgA, IgE, IgG

Question 5

Type of lymphocyte involved in immunologic memory

Answer 5

B-cells persists and accelerate future response to antigen

Question 6

Type of T-cell immunity

Answer 6

Cell-mediated immunity

Question 7

T-cell that aids B-cells

Answer 7

CD4+ T-cells: help B-cells make antibodies

Question 8

Function of CD4+ T-cells

Answer 8

Help B-cells make antibodies and produce cytokines to recruit phagocytes and activate other leukocytes

Question 9

T-cell involved in killing virally infected cells

Answer 9

CD8+ T-cell

Question 10

Type of hypersensitivity reaction T-cell involved in

Answer 10

Delayed cell-mediated hypersensitivity (type IV)

Question 11

T-cells implicated in what type of organ rejection

Answer 11

Acute and chronic cellular organ rejection

Question 12

MHC-II reacts with what T-cell

Answer 12

CD4+ T-cell

Question 13

MHC-I reacts with what T-cell

Answer 13

CD8+ T-cell

Question 14

Function of mature, naive B-cells

Answer 14

Prior to activation express IgM, IgD on their surfaces

Question 15

Site of differentiation of B-cells

Answer 15

Germinal centers of lymph nodes