Recombinant cytokines and clinical uses Flashcards
Erythropoietan recombinant cytokine used in anemias (especially in renal failure)
Epoetin alpha
IL2 recombinant cytokine used in renal cell carcinoma and metastatic melanoma
Aldesleukin
G-CSF recombinant cytokine used in recovery of bone marrow and WBC counts by granulocyte stimulation
Filgrastim
GM-CSF recombinant cytokine used in recovery of bone marrow and WBC counts by granulocyte and monocyte stimulation
Sargramostim
Recombinant cytokine used in chronic hepatitis B and C, Kaposi sarcoma, malignant melanoma, hairy cell leukemia, condyloma acuminata, and renal cell carcinoma
INF-alpha
Recombinant cytokine used in multiple sclerosis
IFN-beta
Recombinant cytokine used in CGD
IFN-gamma
Thrombopoietin analog recombinant cytokine used in thrombocytopenia
Romiplostim
Thrombopoietin receptor agonist recombinant cytokine used in thrombocytopenia
Eltrombopag
IL-11 recombinant cytokine used in thrombocytopenia
Oprelvekin