11 - Derm - Acne - Mgmt of Acne Flashcards Preview

CP2 > 11 - Derm - Acne - Mgmt of Acne > Flashcards

Flashcards in 11 - Derm - Acne - Mgmt of Acne Deck (12):
1

1st 2nd and 3rd line?

1 - topical
2 - systemic treatment
3 - systemic retinoids

2

1st line - for what acne? 3 types?

in mild mod acne
top retinoids/antibacterials/antibiotics

3

topical retinoids - eg? mechanism? 4 SE?

isotretinoin
comedolytic
erythema, irritation, photosensitivity, teratogenic

4

topical antibacterials - do 2 things? eg? may cause what SE? how to get?

antibact + anti- inflam
benzoyl peroxide BPO
dryness, irritation
available otc

5

topical ABs - 2 eg? what is a problem? how to limit?

clindamycin, erythromycin
resistance - use for less than 6m
BPO combined reduces resistance

6

2 nd line - what acne? (3 things) a principle of this treatment line? 2 treatments?

in mod/sev - top treatment failure, scarring, back/chest involvement
combine and maintain remission with topical agents

systemic antibiotics and hormonal treatments

7

hormonal tx - esp when? caution if? eg?

OCP
esp if menstrual cycle related
caution if FHx/venous thrombosis risk

8

systemic ABs - dont do what? why? continue for how long?

dont mix ABs, to avoid resistance
6 weeks to assess effectiveness

9

systemic ABs - 3 lines? 1st line contraindications?

1 - clycines - doxy - CI - preg, breast feeding, children <12
2 - erythromycin
3 - trimethoprim

10

syst retinoids - mechanism? when used?

reduces seb gland size, sebum prod, and comedogenesis
used in tx res acne, nodulocystic, scarring, psych problems

11

syst retinoids SE

dry skin, dry eyes, dry mucosa, epistaxis
lipid and LFT disturbance
arthralgia, myalgia, depression

12

syst retinoids - length? relapse rate? teratogenic.. so what monitoring etc?

for 4-6 months
20-30% relapse
OCP req for 1 month either side and monthly preg tests

Decks in CP2 Class (339):