4 - Obs - Infections in Pregnancy - Infections Flashcards Preview

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Flashcards in 4 - Obs - Infections in Pregnancy - Infections Deck (12):
1

CMV - ?% maternal infection rate. 40% ?? rate
-maternal diagnosis from ? and ? avidity
-fetal diagnosis from ? at 20+ weeks
-10% of affected fetuses ? affected
-? common
-no ?, screening or ?
-10% ? at birth
-develop severe ? sequelae eg hearing, ? and ? impairment or will ?
-most are not seriously affected
-what is offered?

1
vertical trans
IgM + IgG
amniocentesis
severely
deafness
trt, vaccine
aSx
neuro
mental, visual
die
TOP

2

Rubella -
most women are ?, so it is ?
? percent of fetuses affected if weeks - ? offered
- screening IDs those in need of ? immunization
-early preg infection freq causes ? fetal abnoms incl ?, ? disease, eye problems and ? retardation

immune
rare
high
16
TOP
postnatal
multiple
deafness
cardiac
mental

3

Toxoplasmosis - ? percentage of fetuses ? affected.
-Screening not ? in UK
-Maternal Dx from ?
-fetal from ? at 20+ weeks
-proven infection trtd with ?
-fetal toxo trt with ? therapy
-earlier = more ? eg mental retardation, ?, ? and visual impairment
-may do what??

low
permanently
routine
IgM
amnio
spiramycin
combo
severe
convulsions
spasticity
TOP

4

Syphilis - rare
-screening ? because trt prevents ? syphilis
-active disease in preg -> ?, severe ? disease or ?
-trt with prompt ?

routine
congenital
miscarriage
congenital
stillbirth
prompt benzylpenicillin

5

Herpes simplex virus - common
-? infection rare but ?
-? risk of neonatal ? if primary infection within ? weeks of delivery (therefore a ?? is indicated)
-drug of choice? given to who?
-it is not ?
-diagnosis is usually clear ?
-mgmt: refer to ???, risk v low if ? infection present

neonatal
serious
high
herpes
6
C/s
aciclovir - to neonate and mother (in late preg)
teratogenic
clinically
GUM
recurrent

6

GBS - high maternal ? rate - major cause of ? neonatal illness.
Trt with ? penicillin of ?-? groups +/- positive ? trimester screen greatly ? neonatal infection
- how is vert trans prevented?
-trt is RFs for ?? or if ? found incidentally (no screening in UK)

carrier
intrapartum
high-risk
3rd
reduces
IV penicillin
vert trans
GBS

7

GAS - common cause of ??, occasionally causes ..
1 - severe illness in ? with ?
2 - ? sepsis
-most common bacterium ass w ? death - ? is leading cause
-infected fetus often ? in utero and ? ensues
-trt - ? and supportive therapy

sore throat
preg with chorioamnionitis
puerperal
maternal
sepsis
dies
labour
ABx

8

Herpes zoster - many are ?
-severe ? illness in ?
-infection weeks occasionally teratogenic
-infection just before ? can cause severe ? infection - so ? given to ?

immune
maternal
preg
20
delivery
neonatal
IgC
neonate

9

Hep B - carriage common in ?-? women. High ? rate,
-high ? disease rate and ? in neonate
-universal ? ID's neonates in need of ?
-neonatal ? reduces risk of infection by >90%

high-risk
transmission
chronic
mortality
screening
immunoglobulin
immunization

10

Chlamydia - ?% in pregnancy
-neonatal ? and ? labour
-ABx may prevent ??
so screening probably worthwhile
-trt with ? or ?

5%
conjunctivitis
preterm
preterm labour
azithro/erythromycin

11

BV - common
-ass with ? ?
-? and ? if previous preterm labour
-late ? also increased
-trt = oral ?

preterm labour
screening and trt
miscarriage
clindamycin

12

Parvovirus - fetus develops ? and subsequent ?
-if IgM ?, surveillance for ? with middle ? artery ? and ultrasound. ? ? transfusion if anaemia ?

anaemia
hydrops
+ve
anaemia
cerebral
doppler
in utero
severe

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