Cell cycle Flashcards
1
Q
‘resting’ phase
quiescent cells such as hepatocytes and more permanently resting cells such as neurons
A
G0
2
Q
Gap 1
cells increase in size
determines length of cell cycle
under influence of p53
A
G1
3
Q
What regulatory proteins are involved in G1 phase of the cell cycle
A
Cyclin D / CDK4
Cyclin D / CDK6
Cyclin E / CDK2
regulates transition from G1 to S phase
4
Q
Synthesis of DNA, RNA and histone
centrosome duplication
A
S phase
5
Q
What regulatory proteins are involved in S phase?
A
Cyclin A / CDK2
6
Q
Gap 2, cells continue to increase in size
A
G2
7
Q
Regulatory proteins involved in G2
A
Cyclin B / CDK1: regulates transition from G2 to M phase
8
Q
Mitosis - cell division
the shortest phase of the cell cycle
A
M phase
9
Q
Which phase of the cell cycle determines the length of the cycle?
A
G1
