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Question 1

CO2 and ICP relationship

Answer 1

drop in CO2 levels lead to vasoconstriction in brain, hyperventilation is used to treat high ICP

Question 2

overdose of antipsychotics leads to…

Answer 2

neuroleptic malignant syndrome, treat with dantrolene

Question 3

tamoxifen location of action

Answer 3

• inhibitory in breast

- activating in endometrium

Question 4

hirsutism and OCPs

Answer 4

OCPs suppress LH secretion leading to decrease in androgen production

Question 5

Rb

Answer 5

regulates G1 to S phase transition

- active and bound to EF2 when hypophosphorylated, inactive when phosphorylated (lead to synthesis of DNA)

Question 6

three treatments for c diff

Answer 6

fidaxomicin (inhibits RNA polymerase), metronidazole and vancomycin

Question 7

opioid withdrawal symptoms

Answer 7

“wet and sticky”

- nausea, vomiting, cramping, dilated pupil, yawning