4/5 Flashcards

1
Q

immune effects of glucocorticoids

A
  • block phospholipase A2
  • block NFkB
  • decreases T and B cells (T is most important)
  • blacks neutrophil adhesion (increases counts)
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2
Q

rhus dermatitis

A

same as poison ivy

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3
Q

degrees of burns

A
  • first = only epidermis, no blistering, red
  • second = into dermis, blistering
  • third = full dermis, white, no pain
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4
Q

pyloric stenosis vs immature LES

A

pyloric stenosis = olive shaped mass and projectile vomiting
LES = no findings on exam, small volume vomiting

  • both common causes of newborn vomiting
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5
Q

closure of neural tube

A

by week 4

- most teratogens cause damage in weeks 3-8

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6
Q

trypanosoma brucei

A

African sleeping sickness

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7
Q

trypanosoma cruzi

A

Chagas disease, in South/Central America

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8
Q

cold induced duiresis

A

cold causes blood to leave periphery and enter circulation

- high ANP, low ADH leads to diuresis

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9
Q

squamous cell carcinoma in situ

A

actinic keratosis

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10
Q

side of MLF

A

ride MLF controls right adduction and left MLF controls left adduction

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11
Q

warfarin factors

A

2, 7, 9, 10 protein C and S

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12
Q

first factor to be decreased after warfarin

A

7

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13
Q

mechanism of menopause

A
  • age related decrease in follicles
  • lower estrogen production which is normal produced by granulosa cells in follicles
  • very high FSH, high LH, low estrogen
  • causes hot flashes, etc
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14
Q

blood gas in COPD

A

high CO2, low O2, high bicarb for respiratory acidosis compensation

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15
Q

RBC disorder where treatment is splenectomy

A

spherocytosis

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16
Q

seteroline

A

SSRI

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17
Q

treatment for ethylene glycol poisoning

A

fomepizole

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18
Q

order of puberty in girls

A

boobs, pubes and menarche

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19
Q

epimere and hypomere

A
epimere = erector spinae and intervertebral muscles
hypomere = everything else
20
Q

HTLV

A

causes T cell leukemia and lymphoma (mycosis fungoides)

21
Q

transcobalamin

A

R factor - binds B12

- produced in salivary glands

22
Q

complication of levothyroxine

A

atrial fibrillation due to increased beta activation

23
Q

acetyl CoA carboxylase

A

first step in FA synthesis, conversion of acetyl CoA to malonyl CoA

24
Q

deficient enzyme in Fabry’s

A

galactosidase

25
Q

major complication in Fabry’s

A

progressive renal failure, CV disease

26
Q

treatment for homocysteinuria

A

B6 (cofactor)

27
Q

PCP MOA

A

NMDA antagonist

28
Q

pupil in CNIII injury

A

damage to parasympathetics, dilated pupil

29
Q

ovarian tumor resembling glomerulus

A

yolk sac tumor

30
Q

causes of sensorineural hearing loss

A
  • Meniere’s disease
  • acoustic neuroma
  • longstanding noise exposure
  • otitis interna
31
Q

cocaine can cause (heart)

A

coronary vasospasm

32
Q

irregular bleeding and thyroid

A

hypothyroidism, can also cause constipation

33
Q

caffeine MOA

A

antagonism of adenosine in CNS

34
Q

drug for aplastic anemia

A

methimazole

35
Q

carvedilol

A

is a beta blocker with some alpha effects

36
Q

retinitis pigmentosum

A
  • inherited
  • rods affected leading night blindness
  • bone spicule shapes
  • starts in periphery
37
Q

Kluver Bucy syndrome

A

amygdala lesion

38
Q

breathlessness in pregnancy

A

increase in minute ventilation due to increase in tidal volume

39
Q

coughing with vomiting

A

pertussis

40
Q

diagnosis of h pylori

A

scope or urease breath test

41
Q

cystic hygroma

A

Turner syndrome

42
Q

drugs to treat brain tumors

A

nitrosureas

43
Q

demeclocycline

A

ADH antagonist

44
Q

hypocalcemia in blood transfusions

A

due to citrate chelation

45
Q

breast cancer treatment in patient with history of endometrial cancer

A

aromatase inhibitor = anastrozole

46
Q

treatment of viral pericarditis

A

NSAID

47
Q

resistance in strep pneumo

A

alteration of PBP