Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 1 > Test 59 > Flashcards

Test 59 Flashcards

1
Q

central event in pathogenesis of acute necrotizing pancreatitis

A

abnormal activation of trypsinogen to trypsin>

premature activation of zymogens and pancreatic autodigestion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

lower total cholesterol and LDL levels

most effective lipid lowering drugs for primary and secondary prevention of CVD events

A

statins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

manifests in infants w/ ACUTE RENAL FAILURE, microangiopathic hemolytic anemia and thrombocytopenia

decreased RBC
hematocrit
platelet count

A

HUS

increased bleeding time, LDH, BUN, Cr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

interferons a and B

A

produced in response to VIRAL infections

act on neighboring cells>
stimulate them to synthesize antiviral proteins that DEGRADE intracellular mRNA na dimpair protein syntehsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ifn y

A

NK and T cells

promotes Th1 differentiation, MHCII expression, activates mphages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MCC of subungal splinter hemorrhages

A

microemboli from valvular vegetations of bacterial endocarditis

*may hear new onset regurgitant murmur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

used to treat MOST seizure types and are broad spectrum anticonfulsants

A

lamotrigine
levetiracetam
topiramate
valproic acid*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

JME

A

juvenile myoclonic epilepsy

myoclonic seizures that are a form of generalized epilepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Baclofen

A

GABA-B agonist

x muscle spasticity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Baclofen

A

GABA-B agonist

tx muscle spasticity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Clonidene

A

alpha 2 receptor agonist

children w/ ADD who failed tx w/ stimulants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Diazepam

A

used ACUTELY to tx PROLONGED seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DA antagonist that can treat Tourettes

A

fluphenazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

CO poisoning

A
  1. binds Hb w/ more affinity than O2, and reduces number of heme binding sites available to O2–> decrease O2 content in blood
  2. causes LEFT shift of Hb-O2 curve, reflecting decreased tendenccy of O2 to unload in tissues

**does NOT affect PaO2 (O2 dissolved in plasma) NORMAL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Methemoglobinemia

A

drug exposures

Fe2 oxidized to Fe3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
recurrent veginal Candida infections
weight loss
diarrhea
generalized lymphadenopathy
thrush
A

HIV

17
Q

pts w/ AIDS have increased incidence of waht cancer

A

EBV assocaited lymphomas

18
Q

what vitamins are NOT present in breast milk

A

vits D and K

K supplemented by intramuscular injection at delivery to prevent hemorrhagid disease of newborn

vit D supplements hsould be given to prevent rickets d/t lack of sun exposure

19
Q

black pigment stones

A

chronic extravascular hemolysis

20
Q

what drug in combination w/ lisinopril is most likely to cause hyperkalemia

A

K sparing diuretics

21
Q

amiloride
triamterene
spironolactone

A

K sparing diuretics

22
Q

Ticlodopine SE

A

Neutropenia
fever and mouth ulcers

CBC should be monitored biweekly for tfirst three months

23
Q

used to control sxs of carcinoid syndrome

A

octreotide

synthetic STTT analog

24
Q

ondansetron

A

antiemetic used in pts undergoing chemo

5HT3 receptors

25
Q

ondansetron

A

antiemetic used in pts undergoing chemo

5HT3 receptors

26
Q

MCC of ca kidney stone disease

A

Idiopathic hypercalciuria

NORMAL serum Ca levels and high leels of Ca excreted in urine

27
Q

HUS etiology

A

shiga toxin producing gbacteria

E. coli
shigella

28
Q

antecedent diarrheal illness (bloodY)
hemolytic anemica w/ shistocytes
thrombocytopenia
acute kidney injury (red urine)

A

HUS

toxins injure endothelium of preglomerular arterioles/capillaries leading to platelet activation and aggregation to form MICROTHROMBI

29
Q

IgA mediated vasculitis

A

HSP

palpable purpura
abdominal pain
arthralgias
acute glomerulopnephritis

30
Q

streptococcal Ag associated glomerular damage

A

1-3 weeks after infection

31
Q

vasculitis of medium arteries

A

kawasaki disease

32
Q

massive widespread activation of coagulation cascade

A

DIC

d/t release of procoag substances by sepsis, malignancy, trauma

33
Q

hematogneous osteomyelitis

A

MC in children
affects METAPHYSIS of long bones d/t slower blood aflow in region>
chronic supprative osteomyelitis

34
Q

homogenous deposition of eosinophilic hyaline material in intima and media of small arteries and arterioles

A

hyaline arteriosclerosis d/t longstanding non malig HTN or diabetes

35
Q

resembles clinical presentation of Friedrich ataxia

ataxia
dysarthria
loss of P/V sensation

A

severe vit E def

degeneration of spinocerebellar tracts, dorsal column and peripheral nerves

36
Q

vaccination for Rubella

A

live attenuated rubella virus vaccine

Step 1 (69 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions